Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn’s Disease
Joint Authors
Tarocchi, Mirko
Galli, Andrea
Mello, Tommaso
Roselli, Jenny
Innocenti, Tommaso
Parisio, Laura
Macrì, Giuseppe
Milla, Monica
Lynch, Erica Nicola
Milani, Stefano
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-29
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Azathioprine is a cornerstone of the therapy of Crohn’s disease.
Unfortunately, infections and malignancies are relatively common adverse effects related to this drug; however, cirrhosis is exceptionally reported as a side effect.
We report the case of a 49-year-old male patient with ileocolonic steno-penetrating Crohn’s disease who developed hepatic cirrhosis while treated with azathioprine.
After taking azathioprine for 3 years with regular follow-up, he developed pancytopenia, and liver cirrhosis was diagnosed with ultrasound, abdomen computed tomography scan, transient elastography, and liver biopsy.
As all other causes of liver damage were excluded, azathioprine was believed to be the cause of liver injury and therefore was interrupted.
American Psychological Association (APA)
Roselli, Jenny& Innocenti, Tommaso& Lynch, Erica Nicola& Parisio, Laura& Macrì, Giuseppe& Milla, Monica…[et al.]. 2020. Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn’s Disease. Case Reports in Gastrointestinal Medicine،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1147414
Modern Language Association (MLA)
Roselli, Jenny…[et al.]. Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn’s Disease. Case Reports in Gastrointestinal Medicine No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1147414
American Medical Association (AMA)
Roselli, Jenny& Innocenti, Tommaso& Lynch, Erica Nicola& Parisio, Laura& Macrì, Giuseppe& Milla, Monica…[et al.]. Increased Risk of Liver Cirrhosis during Azathioprine Therapy for Crohn’s Disease. Case Reports in Gastrointestinal Medicine. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1147414
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147414