Management of Liddle Syndrome in Pregnancy: A Case Report and Literature Review
Joint Authors
Imran, N.
Alsamsam, Adham
Awadalla, Michael
Patwardhan, Manasi
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Liddle syndrome is an autosomal dominant genetic condition that causes hypertension and hypokalemia due to a gain-of-function mutation in the SCNN1B or SCNN1G genes which code for the epithelial sodium channel in the kidney.
This leads to increased sodium and water reabsorption causing hypertension.
We report a case of a 27-year-old pregnant woman who was admitted for hypertension and hypokalemia and later diagnosed and treated for Liddle syndrome using amiloride.
Maintaining a high suspicion of Liddle syndrome in pregnancy is essential in such cases to be able to adequately and effectively treat the hypertension.
Due to physiological effects of pregnancy, the dose of amiloride may need to be increased as gestational age progresses up to a maximum dose of 30 mg orally per day.
American Psychological Association (APA)
Awadalla, Michael& Patwardhan, Manasi& Alsamsam, Adham& Imran, N.. 2017. Management of Liddle Syndrome in Pregnancy: A Case Report and Literature Review. Case Reports in Obstetrics and Gynecology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147441
Modern Language Association (MLA)
Awadalla, Michael…[et al.]. Management of Liddle Syndrome in Pregnancy: A Case Report and Literature Review. Case Reports in Obstetrics and Gynecology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147441
American Medical Association (AMA)
Awadalla, Michael& Patwardhan, Manasi& Alsamsam, Adham& Imran, N.. Management of Liddle Syndrome in Pregnancy: A Case Report and Literature Review. Case Reports in Obstetrics and Gynecology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147441
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147441