Severe Preeclampsia in the Setting of Myasthenia Gravis
Joint Authors
Al Khabbaz, Antoun
Lake, Adam J.
Keeney, Renée
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-09
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Myasthenia gravis (MG) is a rare autoimmune disease that leads to progressive muscle weakness and is common during female reproductive years.
The myasthenic mother and her newborn must be observed carefully, as complications during all stages of pregnancy and the puerperium may arise suddenly.
Preeclampsia is a common obstetrical condition for which magnesium sulfate is used for seizure prophylaxis.
However, magnesium sulfate is strongly contraindicated in MG as it impairs already slowed nerve-muscle connections.
Similarly, many first-line antihypertensive medications, including calcium channels blockers and β-blockers, may lead to MG exacerbation.
This case describes the effective obstetrical management of a patient with MG who developed severe preeclampsia.
The effective use of levetiracetam and various antihypertensive medications including intravenous labetalol is described.
A review of the ten reported cases of MG complicated by preeclampsia is examined to aggregate observations of clinical care, with focus on delivery methods, anticonvulsants, and antihypertensive medications.
American Psychological Association (APA)
Lake, Adam J.& Al Khabbaz, Antoun& Keeney, Renée. 2017. Severe Preeclampsia in the Setting of Myasthenia Gravis. Case Reports in Obstetrics and Gynecology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1147545
Modern Language Association (MLA)
Lake, Adam J.…[et al.]. Severe Preeclampsia in the Setting of Myasthenia Gravis. Case Reports in Obstetrics and Gynecology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1147545
American Medical Association (AMA)
Lake, Adam J.& Al Khabbaz, Antoun& Keeney, Renée. Severe Preeclampsia in the Setting of Myasthenia Gravis. Case Reports in Obstetrics and Gynecology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1147545
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147545