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Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries
Joint Authors
Urabe, Satoshi
Tanaka, Norifumi
Kudo, Yoshiki
Teraoka, Yuko
Miyoshi, Hiroshi
Oshima, Kumi
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Fibrinogen is an essential agent involved in maintaining pregnancy and coagulation.
Since inherited fibrinogen disorders introduce greater risks for conditions such as placental abruption and postpartum hemorrhage, careful prenatal and perinatal management is essential for this patient population.
We report two cases of successful deliveries in patients with hypofibrinogenemia.
Case 1 is of a 26-year-old (gravida 1, para 1) woman.
The patient’s fibrinogen level increased spontaneously to higher than 300 mg/dL during pregnancy, without treatment.
She delivered at week 38 of gestation, with no complications.
Case 2 is of a 30-year-old (gravida 3, para 1) woman.
We performed repeated infusions of fibrinogen to maintain the level higher than 100 mg/dL during pregnancy and at least 200 mg/dL in the perioperative period; the patient delivered a healthy infant.
We identified a new mutation, Hiroshima I (γ278Tyr→His).
It is important to maintain appropriate fibrinogen levels in cases of inherited fibrinogen disorders for successful prenatal and peripartum management.
American Psychological Association (APA)
Teraoka, Yuko& Miyoshi, Hiroshi& Oshima, Kumi& Urabe, Satoshi& Tanaka, Norifumi& Kudo, Yoshiki. 2017. Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries. Case Reports in Obstetrics and Gynecology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147554
Modern Language Association (MLA)
Teraoka, Yuko…[et al.]. Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries. Case Reports in Obstetrics and Gynecology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147554
American Medical Association (AMA)
Teraoka, Yuko& Miyoshi, Hiroshi& Oshima, Kumi& Urabe, Satoshi& Tanaka, Norifumi& Kudo, Yoshiki. Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries. Case Reports in Obstetrics and Gynecology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147554
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147554