Multiple Myeloma in a Young Female Presenting with Neurological Symptoms
Joint Authors
Lee, Matthew
Zhang, Xinmin
Nguyen, Vinh
Hartley-Brown, Monique
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Multiple myeloma is overall the 14th most common malignancy but is rarely seen in those younger than 35 years.
Those in the younger age group have been shown to have a more aggressive course but reportedly have had similar responses to treatment compared to older cohorts.
Extramedullary plasmacytomas are discrete soft tissue masses of neoplastic monoclonal plasma cells that often occur in patients with multiple myeloma.
Case.
This case entails a young female with new diagnosis of multiple myeloma and multiple extramedullary plasmacytomas presenting with neurological symptoms.
She was treated with CyBorD regimen but was refractory and progressed.
Treatment was changed to DCEP regimen, and daratumumab was added for primary refractory myeloma.
The patient improved rapidly.
Conclusion.
This is a unique case of multiple myeloma in a young female that had failed first-line treatment but responded to targeted therapy of daratumumab.
It highlights that multiple myeloma may present atypically in young patients.
More research is needed on appropriate initial diagnosis and treatment of patients in this age group.
American Psychological Association (APA)
Lee, Matthew& Zhang, Xinmin& Nguyen, Vinh& Hartley-Brown, Monique. 2020. Multiple Myeloma in a Young Female Presenting with Neurological Symptoms. Case Reports in Hematology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1147613
Modern Language Association (MLA)
Lee, Matthew…[et al.]. Multiple Myeloma in a Young Female Presenting with Neurological Symptoms. Case Reports in Hematology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1147613
American Medical Association (AMA)
Lee, Matthew& Zhang, Xinmin& Nguyen, Vinh& Hartley-Brown, Monique. Multiple Myeloma in a Young Female Presenting with Neurological Symptoms. Case Reports in Hematology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1147613
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147613