External Beam Radiation and Brachytherapy for Prostate Cancer: Is It a Possible Trigger of Large Cell Neuroendocrine Carcinoma of the Urinary Bladder?
Joint Authors
Al-Share, Bayan
Kollepara, Sri
Vakhariya, Cynthia
Zakaria, Ali H.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Neuroendocrine tumors commonly involve the respiratory and gastrointestinal systems.
Primary genitourinary neuroendocrine tumors are rare, accounting for less than 1% of all bladder carcinomas.
Four histopathologic subtypes have been described.
Among those, large cell neuroendocrine carcinoma (LCNEC) is the least common, is more aggressive, and generally presents in an advanced stage with poor prognosis compared to transitional cell bladder carcinoma.
There is no standardized treatment regimen because of the rarity of the disease.
Herein, we present a case of 72-year-old male patient with previously treated prostate cancer, who received external beam radiation therapy and high dose brachytherapy, presenting with intermittent hematuria.
Cystoscopy and transurethral resection of bladder tumor (TURBT) were performed.
The histopathology and immunohistochemistry were consistent with large cell neuroendocrine carcinoma (LCNEC).
Further studies are required to proof the higher risk of neuroendocrine carcinoma of the bladder in patients treated with external beam radiation therapy and brachytherapy for prostate cancer.
American Psychological Association (APA)
Zakaria, Ali H.& Al-Share, Bayan& Kollepara, Sri& Vakhariya, Cynthia. 2017. External Beam Radiation and Brachytherapy for Prostate Cancer: Is It a Possible Trigger of Large Cell Neuroendocrine Carcinoma of the Urinary Bladder?. Case Reports in Oncological Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147620
Modern Language Association (MLA)
Zakaria, Ali H.…[et al.]. External Beam Radiation and Brachytherapy for Prostate Cancer: Is It a Possible Trigger of Large Cell Neuroendocrine Carcinoma of the Urinary Bladder?. Case Reports in Oncological Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147620
American Medical Association (AMA)
Zakaria, Ali H.& Al-Share, Bayan& Kollepara, Sri& Vakhariya, Cynthia. External Beam Radiation and Brachytherapy for Prostate Cancer: Is It a Possible Trigger of Large Cell Neuroendocrine Carcinoma of the Urinary Bladder?. Case Reports in Oncological Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147620
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147620