Complete Response to Sorafenib Rechallenge in a Patient with Metastatic Renal Cell Carcinoma
Joint Authors
Kasahara, Ryo
Nakaigawa, Noboru
Kobayashi, Kazuki
Source
Case Reports in Oncological Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-20
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 79-year-old Japanese man underwent a medical examination for hoarseness.
Computed tomography revealed a left renal tumor, and radical nephrectomy was performed.
The tumor was a clear cell carcinoma.
Fourteen months after the operation, the tumor had metastasized to the spleen, right lung, and retroperitoneal lymph nodes.
We initiated molecular targeted therapy sequentially with sorafenib, sunitinib, and axitinib and then conducted a rechallenge with sorafenib.
His metastatic lesions had completely vanished 5 months after initiation of the rechallenge.
Ten months after the rechallenge, lumbar vertebral body metastasis appeared.
However, we consider that the sorafenib rechallenge was effective because of the very slow growth of the metastatic lesion, with no other metastasis for 30 months, at the time of writing this report.
Approximately 7 years after the first local recurrence, he remained alive, with relatively normal daily functioning.
American Psychological Association (APA)
Kasahara, Ryo& Nakaigawa, Noboru& Kobayashi, Kazuki. 2017. Complete Response to Sorafenib Rechallenge in a Patient with Metastatic Renal Cell Carcinoma. Case Reports in Oncological Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147642
Modern Language Association (MLA)
Kasahara, Ryo…[et al.]. Complete Response to Sorafenib Rechallenge in a Patient with Metastatic Renal Cell Carcinoma. Case Reports in Oncological Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147642
American Medical Association (AMA)
Kasahara, Ryo& Nakaigawa, Noboru& Kobayashi, Kazuki. Complete Response to Sorafenib Rechallenge in a Patient with Metastatic Renal Cell Carcinoma. Case Reports in Oncological Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147642
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147642