Myeloid Sarcomas Causing Unilateral Cranial Nerve Palsies in a Patient with Relapsed Acute Myeloblastic Leukemia
Joint Authors
Mendez-Hernandez, A.
Andrade, X. A.
Upadhyay, S.
Parra-Rodriguez, L. M.
Caldeira, E.
Paz, L. H.
Mann, H.
Zia, M.
Sumoza, L.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Myeloid sarcomas (MS) are a rare manifestation of myeloid malignancies and can often be misdiagnosed, leading to a delay in treatment.
The objective of this clinical case is to highlight the challenges of the clinical presentation and to emphasize the importance of this manifestation ensuring timely diagnosis and therapy.
Here, we present a 43-year-old man who was diagnosed with acute myeloblastic leukemia (AML) after being evaluated for unintentional weight loss, subcutaneous nodules, thrombocytopenia, and anemia.
The patient underwent chemotherapy with complete remission and presented 4 months later with dysphagia and cranial nerve palsies.
Appropriate imaging and biopsy led to a diagnosis of myeloid sarcoma, and a decision was made to begin reinduction chemotherapy for AML achieving a second complete remission although his neurological deficits did not improve.
Our case illustrates the protean presentation of myeloid sarcomas; clinicians should have a high suspicion for MS and remain vigilant when unexplained signs and symptoms arise in the background of a myeloid malignancy although challenges still remain when presentation is de novo.
Advancements in understanding the pathophysiology of MS have been performed but remain not completely understood.
High clinical suspicion, appropriate imaging, biopsy techniques, and expertise are paramount for timely diagnosis and treatment.
American Psychological Association (APA)
Mendez-Hernandez, A.& Andrade, X. A.& Upadhyay, S.& Parra-Rodriguez, L. M.& Caldeira, E.& Paz, L. H.…[et al.]. 2020. Myeloid Sarcomas Causing Unilateral Cranial Nerve Palsies in a Patient with Relapsed Acute Myeloblastic Leukemia. Case Reports in Hematology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147649
Modern Language Association (MLA)
Mendez-Hernandez, A.…[et al.]. Myeloid Sarcomas Causing Unilateral Cranial Nerve Palsies in a Patient with Relapsed Acute Myeloblastic Leukemia. Case Reports in Hematology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147649
American Medical Association (AMA)
Mendez-Hernandez, A.& Andrade, X. A.& Upadhyay, S.& Parra-Rodriguez, L. M.& Caldeira, E.& Paz, L. H.…[et al.]. Myeloid Sarcomas Causing Unilateral Cranial Nerve Palsies in a Patient with Relapsed Acute Myeloblastic Leukemia. Case Reports in Hematology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147649
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147649