Ibrutinib-Associated Cardiac Tamponade with Concurrent Antiplatelet Therapy
Joint Authors
Miatech, Jennifer L.
Hughes, John H.
McCarty, Dillon K.
Stagg, M. Patrick
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Ibrutinib is approved for the first-line treatment of chronic lymphocytic leukemia (CLL).
A well-known side effect of ibrutinib therapy is increased bleeding risk, which ranges from mild mucocutaneous bleeding to rarely life-threatening hemorrhage.
The increased bleeding tendency associated with ibrutinib is thought to be related to its effect on several platelet signaling pathways, which can be exacerbated in the setting of concurrent antiplatelet or anticoagulant therapy.
We present an 82-year-old male with CLL on ibrutinib and concurrent antiplatelet therapy who developed cardiac tamponade due to a hemorrhagic pericardial effusion requiring emergent placement of a pericardial window.
This case further highlights the risk of major bleeding in patients treated with ibrutinib and concurrent antiplatelet therapy.
American Psychological Association (APA)
Miatech, Jennifer L.& Hughes, John H.& McCarty, Dillon K.& Stagg, M. Patrick. 2020. Ibrutinib-Associated Cardiac Tamponade with Concurrent Antiplatelet Therapy. Case Reports in Hematology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147656
Modern Language Association (MLA)
Miatech, Jennifer L.…[et al.]. Ibrutinib-Associated Cardiac Tamponade with Concurrent Antiplatelet Therapy. Case Reports in Hematology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147656
American Medical Association (AMA)
Miatech, Jennifer L.& Hughes, John H.& McCarty, Dillon K.& Stagg, M. Patrick. Ibrutinib-Associated Cardiac Tamponade with Concurrent Antiplatelet Therapy. Case Reports in Hematology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147656
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147656