Gastrointestinal Stromal Tumor Induced Hypercalcemia
Joint Authors
Mirrakhimov, Aibek E.
Bailuc, Stefania
Poddutoori, Padma
Richardson, Aida
Barbaryan, Aram
Source
Case Reports in Oncological Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-06
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Hypercalcemia in patients with cancer is a common laboratory finding affecting up to 44% of that patient population.
1,25-Dihydroxyvitamin D3 mediated hypercalcemia is one of the rare mechanisms of this endocrine emergency in cancer patients.
It is even rarer for solid organ neoplasms to present with hypercalcemia mediated through the production of 1,25-dihydroxyvitamin D3.
We report a case of a 77-year-old female who presented to the hospital with hypercalcemia and later was found to have metastatic gastrointestinal stromal tumor.
There have been only 5 cases of gastrointestinal stromal tumor described in literature resulting in hypercalcemia.
In our case, the mechanism of hypercalcemia was thought to be related to overproduction of 1,25-dihydroxyvitamin by tumor cells.
The patient had a favorable response to imatinib with normalization of serum calcium level.
Unfortunately, she developed fluid retention due to imatinib which was discontinued resulting in relapse of hypercalcemia that was resistant to all other treatment options.
American Psychological Association (APA)
Barbaryan, Aram& Bailuc, Stefania& Poddutoori, Padma& Richardson, Aida& Mirrakhimov, Aibek E.. 2017. Gastrointestinal Stromal Tumor Induced Hypercalcemia. Case Reports in Oncological Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147704
Modern Language Association (MLA)
Barbaryan, Aram…[et al.]. Gastrointestinal Stromal Tumor Induced Hypercalcemia. Case Reports in Oncological Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147704
American Medical Association (AMA)
Barbaryan, Aram& Bailuc, Stefania& Poddutoori, Padma& Richardson, Aida& Mirrakhimov, Aibek E.. Gastrointestinal Stromal Tumor Induced Hypercalcemia. Case Reports in Oncological Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147704
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147704