Chronic Atrophic Gastritis with Negative Intrinsic Factor and Parietal Cell Antibody Presenting as a Severe Hemolytic Anemia
Joint Authors
Baker, K.
Cittolin-Santos, G. F.
Bakos, J. K.
Khalil, S.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A 28-year-old Caucasian male with Hashimoto’s disease and vitiligo presented with two weeks of dizziness on exertion following pharyngitis which was treated with prednisone 40 mg by mouth once a day for five days.
Initial workup revealed anemia, elevated lactate dehydrogenase (LDH), and low haptoglobin.
He underwent workup for causes of hemolytic anemia which was remarkable for a peripheral blood smear with hypersegmented neutrophils and low vitamin B12 levels concerning for pernicious anemia.
Parietal cell and intrinsic factor antibodies were negative, and he then underwent an esophagogastroduodenoscopy with biopsy.
The biopsy was negative for Helicobacter pylori, and the immunohistochemical stains were suggestive of chronic atrophic gastritis.
He was started on vitamin B12 1,000 mcg intramuscular injections daily.
His hemoglobin, LDH, and haptoglobin normalized.
Given the absence of the parietal cell antibody and intrinsic factor antibody, this is a rare case of seronegative pernicious anemia.
American Psychological Association (APA)
Cittolin-Santos, G. F.& Khalil, S.& Bakos, J. K.& Baker, K.. 2020. Chronic Atrophic Gastritis with Negative Intrinsic Factor and Parietal Cell Antibody Presenting as a Severe Hemolytic Anemia. Case Reports in Hematology،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1147760
Modern Language Association (MLA)
Cittolin-Santos, G. F.…[et al.]. Chronic Atrophic Gastritis with Negative Intrinsic Factor and Parietal Cell Antibody Presenting as a Severe Hemolytic Anemia. Case Reports in Hematology No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1147760
American Medical Association (AMA)
Cittolin-Santos, G. F.& Khalil, S.& Bakos, J. K.& Baker, K.. Chronic Atrophic Gastritis with Negative Intrinsic Factor and Parietal Cell Antibody Presenting as a Severe Hemolytic Anemia. Case Reports in Hematology. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1147760
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147760