Acquired von Willebrand Disease Associated with Monoclonal Gammopathy of Unknown Significance
Joint Authors
Poudel, Dilli
Dhital, Rashmi
Basnet, Sijan
Tharu, Biswaraj
Ghimire, Sushil
Mir, Izza
Mohanty, Elan
Lin, Catherine
Source
Case Reports in Oncological Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-01
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We present a case of a 79-year-old male who presented with retroperitoneal hematoma a week after motor vehicle accident.
Prior history and family history of bleeding were nonsignificant.
His activated partial thromboplastin time was found to be prolonged in the emergency department.
Further workup with coagulation studies showed decreased factor VIII, vWF antigen, and vWF:ristocetin cofactor assay, and negative Bethesda assay, indicating acquired von Willebrand disease.
Immunofluorescence to find an underlying etiology was suggestive of MGUS.
Management of AvWD depends on controlling active bleeding and treating the underlying cause.
He was treated with factor VIII, haemate-p, rituximab, two cycles of IVIg, and three weeks of oral steroids.
American Psychological Association (APA)
Basnet, Sijan& Lin, Catherine& Dhital, Rashmi& Mir, Izza& Mohanty, Elan& Tharu, Biswaraj…[et al.]. 2017. Acquired von Willebrand Disease Associated with Monoclonal Gammopathy of Unknown Significance. Case Reports in Oncological Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147900
Modern Language Association (MLA)
Basnet, Sijan…[et al.]. Acquired von Willebrand Disease Associated with Monoclonal Gammopathy of Unknown Significance. Case Reports in Oncological Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147900
American Medical Association (AMA)
Basnet, Sijan& Lin, Catherine& Dhital, Rashmi& Mir, Izza& Mohanty, Elan& Tharu, Biswaraj…[et al.]. Acquired von Willebrand Disease Associated with Monoclonal Gammopathy of Unknown Significance. Case Reports in Oncological Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147900