Rifampicin for Treatment of Cholestatic Pruritus Caused by Drug-Induced Acute Liver Injury as Assessed by the RUCAM Classification
Joint Authors
Ahmadi, Ali R.
Chicco, Maria
van den Berge, Marcel
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A male bodybuilder of 39 years of age developed severe pruritus, nausea, and jaundice after injecting anabolic steroids purchased on the black market.
The patient had no history of liver disease and no risk factors for viral hepatitis.
Extensive laboratory testing, radiographic imaging, and liver biopsy excluded a majority of potential pathologies.
The patient was diagnosed with drug-induced acute liver injury and secondary acute renal failure most likely caused by testosterone purchased on the black market.
The pruritus caused insomnia and significant psychological distress.
Treatment was initiated with cholestyramine and naltrexone for one week with no effect on the pruritus.
Subsequently, all medications were stopped, and rifampicin was started.
Pruritus resolved after starting rifampicin, and liver and kidney function improved rapidly and normalized within 5 months.
American Psychological Association (APA)
Ahmadi, Ali R.& Chicco, Maria& van den Berge, Marcel. 2020. Rifampicin for Treatment of Cholestatic Pruritus Caused by Drug-Induced Acute Liver Injury as Assessed by the RUCAM Classification. Case Reports in Hepatology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147974
Modern Language Association (MLA)
Ahmadi, Ali R.…[et al.]. Rifampicin for Treatment of Cholestatic Pruritus Caused by Drug-Induced Acute Liver Injury as Assessed by the RUCAM Classification. Case Reports in Hepatology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147974
American Medical Association (AMA)
Ahmadi, Ali R.& Chicco, Maria& van den Berge, Marcel. Rifampicin for Treatment of Cholestatic Pruritus Caused by Drug-Induced Acute Liver Injury as Assessed by the RUCAM Classification. Case Reports in Hepatology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147974
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147974