Variceal Bleed and Portal Hypertensive Gastropathy in a Noncirrhotic Patient with Isolated Splenomegaly
Joint Authors
Hasan, S. M. Mahmudul
Dmitriew, Meghan
Leonard, Jennifer
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Portal hypertension caused by cirrhosis is the most common etiology of esophageal varices.
However, abnormalities of the splenoportal axis in the absence of liver disease may also cause portal hypertension resulting in varices.
We report a rare case of esophageal variceal bleed in a noncirrhotic patient with isolated splenomegaly secondary to chronic granulocyte colony stimulating factor (G-CSF) therapy.
The patient is a 26-year-old male with Cohen syndrome who required long-term G-CSF treatment for chronic neutropenia.
He presented with large volume hematemesis and pancytopenia in the setting of known splenomegaly with no evidence of cirrhosis.
An urgent EGD revealed active variceal bleeding and portal hypertensive gastropathy.
The patient was appropriately resuscitated and underwent a successful transjugular intrahepatic portosystemic shunt and CT-guided coil placement for the bleeding varices.
We are the first to report variceal bleed as a complication of long-term G-CSF use, a life-threatening consequence that requires urgent intervention.
American Psychological Association (APA)
Hasan, S. M. Mahmudul& Dmitriew, Meghan& Leonard, Jennifer. 2020. Variceal Bleed and Portal Hypertensive Gastropathy in a Noncirrhotic Patient with Isolated Splenomegaly. Case Reports in Hepatology،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147977
Modern Language Association (MLA)
Hasan, S. M. Mahmudul…[et al.]. Variceal Bleed and Portal Hypertensive Gastropathy in a Noncirrhotic Patient with Isolated Splenomegaly. Case Reports in Hepatology No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1147977
American Medical Association (AMA)
Hasan, S. M. Mahmudul& Dmitriew, Meghan& Leonard, Jennifer. Variceal Bleed and Portal Hypertensive Gastropathy in a Noncirrhotic Patient with Isolated Splenomegaly. Case Reports in Hepatology. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1147977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147977