Hepatocellular Glycogen Accumulation in the Setting of Poorly Controlled Type 1 Diabetes Mellitus: Case Report and Review of the Literature
Joint Authors
Aluko, Atinuke
Enofe, Ikponmwosa
Burch, Jacob
Yam, Julie
Khan, Nazia
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Glycogenic hepatopathy (GH) is the accumulation of glycogen in the hepatocytes and represents a rare complication in patients with diabetes mellitus (DM), most commonly type 1 DM.
We present a case of a 23-year-old woman with a medical history of poorly controlled type 1 DM and gastroesophageal reflux disease (GERD) who presented with progressively worsening right-sided abdominal pain.
Diagnostic workup resulted in a liver biopsy with hepatocytes that stained heavily for glycogen with no evidence of fibrosis or steatohepatitis.
A diagnosis of glycogenic hepatopathy was made, and an aggressive glucose control regimen was implemented leading to resolution of symptoms and improvement in AST, ALT, and ALP.
In addition to presenting this rare case, we offer a review of literature and draw important distinctions between glycogenic hepatopathy and other differential diagnoses with the aim of assisting providers in the diagnostic workup and treatment of glycogenic hepatopathy.
American Psychological Association (APA)
Aluko, Atinuke& Enofe, Ikponmwosa& Burch, Jacob& Yam, Julie& Khan, Nazia. 2020. Hepatocellular Glycogen Accumulation in the Setting of Poorly Controlled Type 1 Diabetes Mellitus: Case Report and Review of the Literature. Case Reports in Hepatology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1147998
Modern Language Association (MLA)
Aluko, Atinuke…[et al.]. Hepatocellular Glycogen Accumulation in the Setting of Poorly Controlled Type 1 Diabetes Mellitus: Case Report and Review of the Literature. Case Reports in Hepatology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1147998
American Medical Association (AMA)
Aluko, Atinuke& Enofe, Ikponmwosa& Burch, Jacob& Yam, Julie& Khan, Nazia. Hepatocellular Glycogen Accumulation in the Setting of Poorly Controlled Type 1 Diabetes Mellitus: Case Report and Review of the Literature. Case Reports in Hepatology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1147998
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1147998