Injection Site Erythema in a Patient on Therapeutic Anticoagulation with Low Molecular Weight Heparin after Mechanical Aortic Valve Replacement: A Rare Presentation of Heparin- and Protamine-Induced Thrombocytopenia
Joint Authors
Holaubek, Caroline
Simon, Paul
Eichinger-Hasenauer, Sabine
Gremmel, Franz
Steinlechner, Barbara
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-10
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Previous exposition to heparin and protamine in patients undergoing cardiopulmonary bypass and postoperative therapeutic anticoagulation with LMWH may lead to the development of heparin-induced thrombocytopenia (HIT) and/or protamine-induced thrombocytopenia (PIT).
This case deals with a rare clinical presentation of circulating IgG antibodies against heparin/platelet factor 4 complexes and heparin/protamine complexes after cardiac surgery.
Ensuing purpura and skin necrosis (blisters) at the injection sites of LMWH and clinical symptoms improved rapidly after replacement of LMWH by an alternative anticoagulant.
The aim of this report is to draw attention to the several different clinical manifestations of heparin- and/or protamine-induced thrombocytopenia and shows a possible course of treatment and recovery.
American Psychological Association (APA)
Holaubek, Caroline& Simon, Paul& Eichinger-Hasenauer, Sabine& Gremmel, Franz& Steinlechner, Barbara. 2020. Injection Site Erythema in a Patient on Therapeutic Anticoagulation with Low Molecular Weight Heparin after Mechanical Aortic Valve Replacement: A Rare Presentation of Heparin- and Protamine-Induced Thrombocytopenia. Case Reports in Immunology،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1148002
Modern Language Association (MLA)
Holaubek, Caroline…[et al.]. Injection Site Erythema in a Patient on Therapeutic Anticoagulation with Low Molecular Weight Heparin after Mechanical Aortic Valve Replacement: A Rare Presentation of Heparin- and Protamine-Induced Thrombocytopenia. Case Reports in Immunology No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1148002
American Medical Association (AMA)
Holaubek, Caroline& Simon, Paul& Eichinger-Hasenauer, Sabine& Gremmel, Franz& Steinlechner, Barbara. Injection Site Erythema in a Patient on Therapeutic Anticoagulation with Low Molecular Weight Heparin after Mechanical Aortic Valve Replacement: A Rare Presentation of Heparin- and Protamine-Induced Thrombocytopenia. Case Reports in Immunology. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1148002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148002