Clinical Features of Four West Nile Virus Cases and Its Molecular Characterization from a South Indian Tertiary Care Hospital
Joint Authors
Mammen, Shoba
Nair, Aiswarya
Kumar, Santhosh
Zonderveni, Zayina
Prabhakar, A. T.
Vijay Prakash, Turaka
Aaron, Sanjith
Alexander, Mathew
Zachariah, Anand
Abraham, Asha Mary
Source
Case Reports in Infectious Diseases
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-16
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
West Nile virus (WNV) is currently a significant reemerging virus of the 21st century.
It belongs to the family Flaviviridae and genus Flavivirus.
Although it is primarily transmitted by the Culex spp of mosquitoes, other routes of transmission are also well defined.
Of eight lineages described, Lineage 1a has been reported from many parts of South India and is known to cause neuroinvasive illness.
Many tests and serological techniques have been described to diagnose WNV infection such as complement fixation, neutralization, heamagglutination inhibition, ELISA, and PCR for molecular confirmation.
The latter far outweighs the limitations inherent in the other tests.
WNV infection is being reported from Vellore for the first time after 1968.
This paper aims to describe four cases of WNV infection causing central nervous system manifestations with its molecular characterization.
West Nile virus infection was diagnosed with the available molecular techniques such as PCR and sequencing, which emphasizes the need for considering West Nile virus in the differential diagnosis of acute meningoencephalitis and the wider availability of molecular diagnostic tests.
American Psychological Association (APA)
Mammen, Shoba& Nair, Aiswarya& Kumar, Santhosh& Zonderveni, Zayina& Prabhakar, A. T.& Vijay Prakash, Turaka…[et al.]. 2020. Clinical Features of Four West Nile Virus Cases and Its Molecular Characterization from a South Indian Tertiary Care Hospital. Case Reports in Infectious Diseases،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1148088
Modern Language Association (MLA)
Mammen, Shoba…[et al.]. Clinical Features of Four West Nile Virus Cases and Its Molecular Characterization from a South Indian Tertiary Care Hospital. Case Reports in Infectious Diseases No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1148088
American Medical Association (AMA)
Mammen, Shoba& Nair, Aiswarya& Kumar, Santhosh& Zonderveni, Zayina& Prabhakar, A. T.& Vijay Prakash, Turaka…[et al.]. Clinical Features of Four West Nile Virus Cases and Its Molecular Characterization from a South Indian Tertiary Care Hospital. Case Reports in Infectious Diseases. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1148088
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148088