Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review
Joint Authors
Evangeliou, Alexandros P.
Ziogas, Ioannis A.
Tsachouridou, Olga
Arvanitaki, Alexandra
Tsona, Afroditi
Kamperidis, Vassilios
Papagianni, Marianthi
Panagiotidis, Theofilos
Tourtounis, Ilias A.
Metallidis, Symeon
Giannakoulas, Georgios
Source
Case Reports in Infectious Diseases
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Blood culture-negative infective endocarditis (BCNIE) can present subtly and is associated with a diagnostic delay leading to increased morbidity and mortality.
Case Report.
We present the case of an 18-year-old male with a history of complex congenital heart disease and 3-year intermittent episodes of fever of unknown origin, who was referred to our hospital for upper and lower extremity focal seizures.
Laboratory blood tests were normal, blood cultures were negative, and brain imaging revealed an abscess.
Cardiology consultation was requested, and transthoracic echocardiography revealed an intracardiac vegetation.
Empiric antibiotic treatment with sultamicillin, gentamycin, and meropenem was initiated.
Serology testing was positive for Coxiella burnetii, and the diagnosis of BCNIE was established.
The antibiotic course was changed to oral doxycycline for 36 months and led to resolution of IE, with no vegetation detected on TTE after 15 months.
Conclusion.
BCNIE is a life-threatening disease entity that can lead to severe complications, such as valve regurgitation, emboli, and death.
Patients with congenital heart disease are particularly vulnerable to IE.
Timely diagnosis and antibiotic management are of paramount importance in order to avoid the potentially fatal sequelae.
American Psychological Association (APA)
Ziogas, Ioannis A.& Evangeliou, Alexandros P.& Tsachouridou, Olga& Arvanitaki, Alexandra& Tsona, Afroditi& Kamperidis, Vassilios…[et al.]. 2020. Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review. Case Reports in Infectious Diseases،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1148228
Modern Language Association (MLA)
Ziogas, Ioannis A.…[et al.]. Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review. Case Reports in Infectious Diseases No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1148228
American Medical Association (AMA)
Ziogas, Ioannis A.& Evangeliou, Alexandros P.& Tsachouridou, Olga& Arvanitaki, Alexandra& Tsona, Afroditi& Kamperidis, Vassilios…[et al.]. Coxiella Endocarditis as the Cause of Recurrent Fever and Brain Abscess in a Patient with Complex Congenital Heart Disease: A Case Report and Literature Review. Case Reports in Infectious Diseases. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1148228
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148228