The Safe Administration of Remdesivir in a Patient with Acute Kidney Injury Requiring Hemodialysis
Joint Authors
Peyko, Vincent
Ladd, Helena
Cutrona, Anthony
Source
Case Reports in Infectious Diseases
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-29
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Remdesivir is a nucleoside analog prodrug with broad-spectrum antiviral activity, including against coronaviruses.
This has prioritized the inclusion of remdesivir in coronavirus disease 2019 (COVID-19) clinical trials.
The United States Food and Drug Administration has granted emergency use authorization for remdesivir.
This emergency use authorization does not recommend the use of remdesivir in patients with estimated glomerular filtration rate (eGFR) less than 30 mL/min unless the benefits outweigh the risks.
To date, there are no studies and scant information in the literature evaluating remdesivir utilization in patients with eGFR less than 30 mL/min or receiving hemodialysis.
With little utilization data for patients with acute or chronic kidney injury, remdesivir may not be considered, leaving this patient population without the opportunity of a potentially beneficial treatment option.
We present a case of one patient with eGFR less than 30 mL/min that required hemodialysis in which remdesivir was safely initiated, with therapy completed without any serious adverse events.
American Psychological Association (APA)
Peyko, Vincent& Ladd, Helena& Cutrona, Anthony. 2020. The Safe Administration of Remdesivir in a Patient with Acute Kidney Injury Requiring Hemodialysis. Case Reports in Infectious Diseases،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1148251
Modern Language Association (MLA)
Peyko, Vincent…[et al.]. The Safe Administration of Remdesivir in a Patient with Acute Kidney Injury Requiring Hemodialysis. Case Reports in Infectious Diseases No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1148251
American Medical Association (AMA)
Peyko, Vincent& Ladd, Helena& Cutrona, Anthony. The Safe Administration of Remdesivir in a Patient with Acute Kidney Injury Requiring Hemodialysis. Case Reports in Infectious Diseases. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1148251
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148251