Autologous Concentrated Bone Marrow Grafting for the Treatment of Osteonecrosis of the Humeral Head: A Report of Five Shoulders in Four Cases
Joint Authors
Yamazaki, Masashi
Mishima, Hajime
Sugaya, Hisashi
Makihara, Takeshi
Yoshioka, Tomokazu
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Five shoulders in four patients affected by advanced osteonecrosis of the humeral head were treated with autologous concentrated bone marrow grafting.
Bone marrow sample was aspirated from the iliac crests, concentrated by a centrifugation technique, and injected into the necrotic site.
The shoulders were evaluated radiologically with X-ray scoring and clinically with measurement of range of motion and pain score (visual analogue scale, VAS).
The mean follow-up period was 49.4 (range, 24–73) months.
The concentration ratio of nucleated cells was calculated and the number of transplanted mesenchymal stem cells (MSC) was estimated by a colony-forming assay.
All four shoulders with stage 3 disease achieved joint sparing.
One shoulder with stage 4 disease required replacement surgery.
Clinical evaluation of the spared joints showed improvement in range of motion in two cases and deterioration in two cases.
VAS scores were 0 after surgery in three cases.
The mean concentration ratio was 2.73, and the mean number of transplanted MSC was 1125.
The outcomes of autologous concentrated bone marrow grafting for advanced osteonecrosis of the humeral head were varied.
Further research is needed to determine the effectiveness and the indications of the present surgery.
American Psychological Association (APA)
Makihara, Takeshi& Yoshioka, Tomokazu& Sugaya, Hisashi& Yamazaki, Masashi& Mishima, Hajime. 2017. Autologous Concentrated Bone Marrow Grafting for the Treatment of Osteonecrosis of the Humeral Head: A Report of Five Shoulders in Four Cases. Case Reports in Orthopedics،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1148314
Modern Language Association (MLA)
Makihara, Takeshi…[et al.]. Autologous Concentrated Bone Marrow Grafting for the Treatment of Osteonecrosis of the Humeral Head: A Report of Five Shoulders in Four Cases. Case Reports in Orthopedics No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1148314
American Medical Association (AMA)
Makihara, Takeshi& Yoshioka, Tomokazu& Sugaya, Hisashi& Yamazaki, Masashi& Mishima, Hajime. Autologous Concentrated Bone Marrow Grafting for the Treatment of Osteonecrosis of the Humeral Head: A Report of Five Shoulders in Four Cases. Case Reports in Orthopedics. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1148314
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148314