Finding the Cause of Psychosis: A Challenging Case of Anti-NMDAR Encephalitis
Joint Authors
Sanivarapu, Raghavendra
Sabbula, Bhanu R.
Yemmanur, Shravya
Kagolanu, Deepthi
Shadab, Ahmed
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
An autoimmune response causing inflammation in the brain tissue is called autoimmune encephalitis.
Autoantibodies directed against N-methyl-D-aspartate (NMDA) receptors cause a type of autoimmune encephalitis resulting in memory loss, confusion, and psychosis.
A 28-year-old male with a history of schizophrenia, seizure disorder, and stroke presented with a 2-day history of bizarre behavior, restlessness, insomnia, agitation, and hallucinations.
He was initially managed for acute psychosis without any improvement.
Further workup for organic causes revealed positive NMDAR antibodies in both the cerebrospinal fluid and serum, confirming a diagnosis of autoimmune encephalitis.
His condition later improved with steroids and intravenous immunoglobulins.
This case signifies the importance of ruling out organic causes in patients with unexplained neuropsychiatric symptoms.
NMDA encephalitis is more common in young females with underlying malignancies, especially ovarian teratomas.
This case is unique, given the extremely rare occurrence of NMDA encephalitis in male patients without any malignancies.
American Psychological Association (APA)
Sabbula, Bhanu R.& Yemmanur, Shravya& Sanivarapu, Raghavendra& Kagolanu, Deepthi& Shadab, Ahmed. 2020. Finding the Cause of Psychosis: A Challenging Case of Anti-NMDAR Encephalitis. Case Reports in Medicine،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148396
Modern Language Association (MLA)
Sabbula, Bhanu R.…[et al.]. Finding the Cause of Psychosis: A Challenging Case of Anti-NMDAR Encephalitis. Case Reports in Medicine No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1148396
American Medical Association (AMA)
Sabbula, Bhanu R.& Yemmanur, Shravya& Sanivarapu, Raghavendra& Kagolanu, Deepthi& Shadab, Ahmed. Finding the Cause of Psychosis: A Challenging Case of Anti-NMDAR Encephalitis. Case Reports in Medicine. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148396
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148396