Effect of vitex agnus-castus extract on some physiological parameters of mice : mus musculus l.

Abstract EN

Vitex (known locally as kaf murium) has a long history of traditional use in women.

The effect of alcoholic extract of vitex agnus-castus was examined for its effect on some blood parameters in mice (Mus Musculus).

Mice in the treatment groups were injected intraperitoneally with two doses (6 mgand12 mg / mouse) of vitex extract while the control group received distilled water daily for two weeks.

Blood parameters (RBC, Hb, PCV) showed a significant decrease with both doses in comparison to the control group (P<0.01), while no significant decrease in (WBC) was found.

Biochemical parameters (total serum protein, total serum cholesterol) showed a significant decrease in the treatment groups as compared with the control group (P<0.01).

In conclusion, vitex agnus-castus alcoholic extract can have a significant adverse effect on blood.

Its cholesterol lowering effect worths investigation in the future.