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A Case of Acute Motor Sensory Axonal Neuropathy: A Variant of Guillain-Barré Syndrome, with Possible Syndrome of Irreversible Lithium-Effectuated Neurotoxicity
Joint Authors
Liu, David Y.
Hollenbach, Jessica R.
Gregorin, Jason A.
Wynbrandt, Jonathan H.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Acute Motor Sensory Axonal Neuropathy (AMSAN) is a rare and severe variant of Guillain-Barré syndrome (GBS) that has a prolonged recovery course.
GBS is often suspected due to ascending muscle weakness, sensation difficulties, respiratory compromise, and antecedent diarrhea.
The diagnosis of GBS is supported by cerebrospinal fluid analysis showing albuminocytologic dissociation.
Electromyogram and nerve conduction study confirm the diagnosis and allow for further classification by variant.
Treatment involves either IV immune globulins or plasmapheresis, and patients typically recover.
However, depending on the variant and severity, patients may ultimately require prolonged mechanical ventilation with tracheostomy.
In these cases, they may continue to have persistent muscle and sensation abnormalities requiring long-term care.
We present a unique case of a 38-year-old female patient with decade-long use of lithium for bipolar disorder that presented with acute lithium toxicity.
Though she was ultimately diagnosed with AMSAN, the Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT) may have also contributed to her persistent neurological sequelae.
American Psychological Association (APA)
Liu, David Y.& Hollenbach, Jessica R.& Gregorin, Jason A.& Wynbrandt, Jonathan H.. 2020. A Case of Acute Motor Sensory Axonal Neuropathy: A Variant of Guillain-Barré Syndrome, with Possible Syndrome of Irreversible Lithium-Effectuated Neurotoxicity. Case Reports in Medicine،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148477
Modern Language Association (MLA)
Liu, David Y.…[et al.]. A Case of Acute Motor Sensory Axonal Neuropathy: A Variant of Guillain-Barré Syndrome, with Possible Syndrome of Irreversible Lithium-Effectuated Neurotoxicity. Case Reports in Medicine No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1148477
American Medical Association (AMA)
Liu, David Y.& Hollenbach, Jessica R.& Gregorin, Jason A.& Wynbrandt, Jonathan H.. A Case of Acute Motor Sensory Axonal Neuropathy: A Variant of Guillain-Barré Syndrome, with Possible Syndrome of Irreversible Lithium-Effectuated Neurotoxicity. Case Reports in Medicine. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148477
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148477