A New Flavanone as a Potent Antioxidant Isolated from Chromolaena odorata L. Leaves
Joint Authors
Putri, Devi Anggraini
Fatmawati, Sri
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-18
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Chromolaena odorata L.
(Asteraceae) is one of the tropical plants which is widely used as traditional medicines for diabetes and soft tissue wounds treatment in some regions in East Indonesia.
The present study was aimed at determining the bioactive compounds of C.
odorata leaves.
The methanol and ethyl acetate extracts of C.
odorata leaves have the inhibitory activity against 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals as well as α-glucosidase rat intestine enzyme.
A new flavanone was isolated from the methanol extract and elucidated as 5,3’-dihydroxy-7,6’-dimethoxyflavanone or, namely, odoratenin (1) together with two known compounds: isosakuranetin (2) and subscandenin (3).
The antioxidant activity of odoratenin (1) exhibited very potent ABTS radical inhibitory activity with IC50 value of 23.74 μM which is lower than that of trolox (IC50 31.32 μM) as a positive control.
The result showed that a new flavanone, odoratenin (1), should be potential as an antioxidant source.
American Psychological Association (APA)
Putri, Devi Anggraini& Fatmawati, Sri. 2019. A New Flavanone as a Potent Antioxidant Isolated from Chromolaena odorata L. Leaves. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1148556
Modern Language Association (MLA)
Putri, Devi Anggraini& Fatmawati, Sri. A New Flavanone as a Potent Antioxidant Isolated from Chromolaena odorata L. Leaves. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1148556
American Medical Association (AMA)
Putri, Devi Anggraini& Fatmawati, Sri. A New Flavanone as a Potent Antioxidant Isolated from Chromolaena odorata L. Leaves. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1148556
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148556
