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Grinspan’s Syndrome: A Rare Case with Malignant Transformation
Joint Authors
Zenginkinet, Tulay
Kökten, Numan
Uzun, Lokman
Karadağ, Ayşe Serap
Kalcioglu, M. Tayyar
Source
Case Reports in Otolaryngology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-04
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Aim.
Oral lichen planus (OLP) is one of the common chronic inflammatory, noninfectious, and precancerous oral mucosal diseases that affect the stratified squamous epithelium in adults.
Grinspan et al.
reported an association of OLP with diabetes mellitus and vascular hypertension and called that Grinspan’s syndrome in 1966.
We aim to present a case of Grinspan’s syndrome with malignant transformation.
Case Presentation.
A 60-year-old man who presented with a ten-year history of OLP diagnosed clinically and histologically was referred to our otolaryngology department with a painless swallowing in the left buccal mucosa for 3 months.
Clinical examination revealed several plaques, striated white lesions in the buccal mucosa bilaterally, and an exophytic tumor in the left buccal mucosa.
Histopathological examination showed lichen planus bilaterally and oral squamous cell carcinoma in the left buccal mucosa.
The tumor had been developed on the preexisting areas of lichen planus which had been histologically proven before.
The tumor was removed completely, and the tissue defect on the buccal mucosa was repaired with a split-thickness skin graft.
Conclusion.
Patients with OLP should be followed up periodically in a long term at close intervals for early diagnosis of malignant transformation.
American Psychological Association (APA)
Kökten, Numan& Uzun, Lokman& Karadağ, Ayşe Serap& Zenginkinet, Tulay& Kalcioglu, M. Tayyar. 2018. Grinspan’s Syndrome: A Rare Case with Malignant Transformation. Case Reports in Otolaryngology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1148589
Modern Language Association (MLA)
Kökten, Numan…[et al.]. Grinspan’s Syndrome: A Rare Case with Malignant Transformation. Case Reports in Otolaryngology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1148589
American Medical Association (AMA)
Kökten, Numan& Uzun, Lokman& Karadağ, Ayşe Serap& Zenginkinet, Tulay& Kalcioglu, M. Tayyar. Grinspan’s Syndrome: A Rare Case with Malignant Transformation. Case Reports in Otolaryngology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1148589
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148589