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Primary Diffuse Large B Cell Lymphoma Mimicking Hyperplastic Reactive Lesion (Lymphoma of the Oral Cavity)
Joint Authors
Couto Souza, Paulo Henrique
Batista Rodrigues Johann, Aline Cristina
Franco, Ademir
Berti-Couto, Soraya de Azambuja
Donaduzzi, Liziane Cattelan
Reinheimer, Angélica
da Silva, Maria Augusta Ramires
de Noronha, Lucia
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
To report a case of a challenging oral diagnosis involving a primary diffuse large B cell lymphoma of the oral cavity mimicking a hyperplastic reactive lesion.
Case Report.
A 72-year-old male patient was referred to the Department of Stomatology presenting a proliferative nodular lesion in the anterior region of the mandible involving the anterior teeth.
The clinical examination revealed anterior teeth affected by periodontal disease, suggesting the nodular cession hyperplastic reaction.
Incisional biopsy was performed under local anesthesia.
The histopathological examination revealed a diffuse proliferation of atypical large lymphoid cells.
The tumor cells showed immunopositivity for CD20 and Ki67 (100%) and negativity for CD3, CD30, and CD15.
The diagnosis of diffuse large B cell lymphoma was established.
The patient underwent chemotherapy and progressed to death after nine months.
Conclusion.
Lymphomas of the oral cavity are rare and may have nonspecific clinical features, mimicking inflammatory and reactive lesions.
Therefore, a detailed clinical evaluation associated with histopathological and immunohistochemical analysis should be performed to enable early and accurate diagnoses in suspected oral lesions.
American Psychological Association (APA)
Donaduzzi, Liziane Cattelan& Reinheimer, Angélica& da Silva, Maria Augusta Ramires& de Noronha, Lucia& Batista Rodrigues Johann, Aline Cristina& Franco, Ademir…[et al.]. 2018. Primary Diffuse Large B Cell Lymphoma Mimicking Hyperplastic Reactive Lesion (Lymphoma of the Oral Cavity). Case Reports in Pathology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1148714
Modern Language Association (MLA)
Donaduzzi, Liziane Cattelan…[et al.]. Primary Diffuse Large B Cell Lymphoma Mimicking Hyperplastic Reactive Lesion (Lymphoma of the Oral Cavity). Case Reports in Pathology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1148714
American Medical Association (AMA)
Donaduzzi, Liziane Cattelan& Reinheimer, Angélica& da Silva, Maria Augusta Ramires& de Noronha, Lucia& Batista Rodrigues Johann, Aline Cristina& Franco, Ademir…[et al.]. Primary Diffuse Large B Cell Lymphoma Mimicking Hyperplastic Reactive Lesion (Lymphoma of the Oral Cavity). Case Reports in Pathology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1148714
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148714