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TLE1 Positive Clear Cell Sarcoma of the Kidney: A Case Report and Review of the Literature
Author
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-16
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Clear cell sarcoma of the kidney (CCSK) is an uncommon malignant tumor of uncertain histogenesis that occurs most commonly in childhood.
Histologically, CCSK can mimic myxoid variant of synovial sarcoma (SS); however, the double positivity for CD99 and TLE1 in SS helps in excluding CCSK.
Herein, we report a rare case of CCSK arising in the left kidney of a 3-year-old girl.
The mass grossly measured 9.5 cm in maximum dimension and histologically showed the classic arborizing fibrovascular septae and background myxoid matrix that is usually seen in CCSK.
The tumor however was double positive for CD99 and TLE1 which made it difficult to discriminate it from the myxoid variant of SS based on histopathological examination and immunophenotype alone, and genetic analysis for SYT gene rearrangement was required to reach a definitive diagnosis.
Although there have been previous case reports of CCSK with positive expression of CD99 and negative TLE1, to our knowledge, this is the first case of CCSK expressing both CD99 and TLE1.
American Psychological Association (APA)
Naous, Rana. 2018. TLE1 Positive Clear Cell Sarcoma of the Kidney: A Case Report and Review of the Literature. Case Reports in Pathology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1148720
Modern Language Association (MLA)
Naous, Rana. TLE1 Positive Clear Cell Sarcoma of the Kidney: A Case Report and Review of the Literature. Case Reports in Pathology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1148720
American Medical Association (AMA)
Naous, Rana. TLE1 Positive Clear Cell Sarcoma of the Kidney: A Case Report and Review of the Literature. Case Reports in Pathology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1148720
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148720