Adult-Type Rhabdomyoma of the Larynx: Clinicopathologic Study of an Uncommon Tumor in a Rare Location
Joint Authors
Greco, A.
Altissimi, Giancarlo
Cianfrone, Giancarlo
Corsi, Alessandro
Ralli, Massimo
Sementilli, Giulio
Fiorentino, Francesco
Ciofalo, Andrea
de Vincentiis, Marco
Source
Case Reports in Otolaryngology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Rhabdomyoma is an uncommon benign mesenchymal tumor with skeletal muscle differentiation that may occur either in the heart or in extracardiac sites.
Even though the head and neck region is the most common area of extracardiac rhabdomyoma, the larynx is rarely involved.
We present the case of an 85-year-old woman who reported a 10-day history of breathing difficulties, dysphagia, and dysphonia.
A computed tomography scan of the head and neck showed a contrast-enhanced, solid hypopharyngeal-laryngeal neoplasm with well-defined margins causing subtotal obliteration of the right pyriform sinus and a reduction in air lumen of the laryngeal vestibule.
The patient underwent complete endoscopic removal of the lesion; histologic examination revealed an adult-type rhabdomyoma based on the histologic features and the immunoreactivity of the neoplastic cells for desmin, myoglobin, and muscle-specific actin but not for cytokeratin, S-100, CD68R, chromogranin-A, and synaptophysin.
Since clinical and imaging features are not specific for rhabdomyoma, histologic examination and immunohistochemical analyses play a central role in the differential diagnosis of the adult-type rhabdomyoma from other laryngeal neoplasms.
A correct diagnosis is mandatory to avoid inappropriate treatment.
American Psychological Association (APA)
Altissimi, Giancarlo& Ralli, Massimo& Sementilli, Giulio& Fiorentino, Francesco& Ciofalo, Andrea& Greco, A.…[et al.]. 2017. Adult-Type Rhabdomyoma of the Larynx: Clinicopathologic Study of an Uncommon Tumor in a Rare Location. Case Reports in Otolaryngology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1148729
Modern Language Association (MLA)
Altissimi, Giancarlo…[et al.]. Adult-Type Rhabdomyoma of the Larynx: Clinicopathologic Study of an Uncommon Tumor in a Rare Location. Case Reports in Otolaryngology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1148729
American Medical Association (AMA)
Altissimi, Giancarlo& Ralli, Massimo& Sementilli, Giulio& Fiorentino, Francesco& Ciofalo, Andrea& Greco, A.…[et al.]. Adult-Type Rhabdomyoma of the Larynx: Clinicopathologic Study of an Uncommon Tumor in a Rare Location. Case Reports in Otolaryngology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1148729
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148729