The Relationship between Werner Syndrome and Sinonasal Malignant Melanoma: Two Sibling Cases of Werner Syndrome with Malignant Melanoma
Joint Authors
Kodama, Satoru
Suzuki, Masashi
Kadowaki, Yoshinori
Moriyama, Munehito
Source
Case Reports in Otolaryngology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Werner syndrome (WS) is an autosomal recessive disease characterized by premature aging.
Malignant tumors such as thyroid carcinoma and malignant melanoma occur frequently in WS patients.
We describe 2 siblings with WS who suffered from sinonasal malignant melanoma (MM).
Both patients initially experienced nasal obstruction and recurrent nasal bleeding and died within 2 years of the diagnosis of MM.
Otolaryngologists should recognize that WS patients have a high risk for head and neck malignant disease, particularly sinonasal MM, even if they are aged below the expected age range and undergo periodic examinations.
Furthermore, it is important that WS patients are aware that a prompt nasal examination is indicated if they experience continuous nasal obstruction or recurrent nasal bleeding.
American Psychological Association (APA)
Kadowaki, Yoshinori& Kodama, Satoru& Moriyama, Munehito& Suzuki, Masashi. 2017. The Relationship between Werner Syndrome and Sinonasal Malignant Melanoma: Two Sibling Cases of Werner Syndrome with Malignant Melanoma. Case Reports in Otolaryngology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1148779
Modern Language Association (MLA)
Kadowaki, Yoshinori…[et al.]. The Relationship between Werner Syndrome and Sinonasal Malignant Melanoma: Two Sibling Cases of Werner Syndrome with Malignant Melanoma. Case Reports in Otolaryngology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1148779
American Medical Association (AMA)
Kadowaki, Yoshinori& Kodama, Satoru& Moriyama, Munehito& Suzuki, Masashi. The Relationship between Werner Syndrome and Sinonasal Malignant Melanoma: Two Sibling Cases of Werner Syndrome with Malignant Melanoma. Case Reports in Otolaryngology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1148779
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148779