Leptospirosis Presenting with Features of Thrombotic Microangiopathy

Joint Authors

Ebad, Chaudhry Adeel
Moollan, Nabeehah
Rafi Ahmed, Adeel
Magee, Colm
Dorman, Anthony

Source

Case Reports in Nephrology

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-11-17

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Leptospirosis is an exceptionally rare infectious disease in the Republic of Ireland.

Leptospirosis can present with or mimic thrombotic microangiopathies (TTP/HUS).

A 48-year-old male presented to a peripheral hospital with a short history of diarrhoea, anaemia, hyperbilirubinemia, raised lactate dehydrogenase, thrombocytopenia, and severe acute kidney injury and was transferred to our tertiary care kidney centre.

A form of acute thrombotic microangiopathy (TMA) was suspected.

However, no schistocytes were seen on the blood film, and the reticulocyte count was depressed.

A kidney biopsy was performed before initiating any potential treatment which revealed acute interstitial nephritis (AIN).

Leptospirosis was considered and subsequently serologically confirmed.

The patient was managed with antimicrobials and supportive therapy.

Acute kidney injury is common in leptospirosis and is often due to AIN.

Initial presentation can mimic TMA; however, a differential diagnosis of leptospirosis should be considered even in nonendemic areas due to re-emergence of the disease.

American Psychological Association (APA)

Ebad, Chaudhry Adeel& Moollan, Nabeehah& Rafi Ahmed, Adeel& Dorman, Anthony& Magee, Colm. 2020. Leptospirosis Presenting with Features of Thrombotic Microangiopathy. Case Reports in Nephrology،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148834

Modern Language Association (MLA)

Ebad, Chaudhry Adeel…[et al.]. Leptospirosis Presenting with Features of Thrombotic Microangiopathy. Case Reports in Nephrology No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1148834

American Medical Association (AMA)

Ebad, Chaudhry Adeel& Moollan, Nabeehah& Rafi Ahmed, Adeel& Dorman, Anthony& Magee, Colm. Leptospirosis Presenting with Features of Thrombotic Microangiopathy. Case Reports in Nephrology. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1148834

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1148834