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A Chinese Prescription Chuanxiong Chatiao San for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Joint Authors
Zou, Jun-Bo
Zhang, Xiao-Fei
Shi, Ya-Jun
Tai, Jia
Wang, Yu
Liang, Yu-Lin
Guo, Dong-Yan
Wang, Mei
Cui, Chunli
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-31
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Backgrounds.
Chuanxiong Chatiao san (CXCT) is a famous Chinese classical prescription.
It has a favorable effect in treating migraine.
It is reported that CXCT combined with Western conventional medicine (WCM) could increase the therapeutic efficacy on migraine.
The purpose of this paper is to systematically assess the clinical efficacy, safety, and some indexes of CXCT for migraine.
Methods.
PubMed, Embase Database, China National Knowledge Infrastructure (CNKI), Wanfang Database, the Cochrane Library, and the CBM were searched from January 2000 to February 2019.
We made a detailed record of outcome measurements.
Meta-analysis was performed using RevMan 5.3 software.
Results.
A total of 3307 patients were included in the 37 articles.
Meta-analysis showed that CXCT significantly increased the total efficiency rate (TER), compared with Western medicine treatment (WMC) (P < 0.00001).
When CXCT is combined with WMC, the result showed that P < 0.00001.
CXCT was significantly reduced the adverse events (AEs) compared with WMC (P < 0.00001).
The levels of VAS, number of migraine episodes (NE), and time of headache duration (TD) were significantly reduced (P < 0.00001).
Platelet function and blood rheology level were improved via a significantly decrease in 5-HT and β-EP (P < 0.00001).
Other indicators such as substance P, CGRP high-cut viscosity, low-cut viscosity, plasma viscosity, and fibrinogen were significantly reduced (P < 0.00001).
Conclusion.
Our findings provide evidence that CXCT and CXCT combined with WMC have higher efficacy in the treatment of migraine compared with WCM alone.
Methodological quality was generally low, so the conclusion of this paper has some limitations and it has to be carefully evaluated.
American Psychological Association (APA)
Wang, Yu& Shi, Ya-Jun& Zhang, Xiao-Fei& Zou, Jun-Bo& Liang, Yu-Lin& Tai, Jia…[et al.]. 2019. A Chinese Prescription Chuanxiong Chatiao San for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-17.
https://search.emarefa.net/detail/BIM-1148876
Modern Language Association (MLA)
Wang, Yu…[et al.]. A Chinese Prescription Chuanxiong Chatiao San for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-17.
https://search.emarefa.net/detail/BIM-1148876
American Medical Association (AMA)
Wang, Yu& Shi, Ya-Jun& Zhang, Xiao-Fei& Zou, Jun-Bo& Liang, Yu-Lin& Tai, Jia…[et al.]. A Chinese Prescription Chuanxiong Chatiao San for Migraine: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-17.
https://search.emarefa.net/detail/BIM-1148876
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148876