Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections
Joint Authors
Palmer, Cheryl Ann
Chen, Ricky
Singh, Gurjeet
McNally, J. Scott
de Havenon, Adam
Source
Case Reports in Neurological Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
Intravascular lymphoma (IVL) is an uncommon and often fatal disease characterized by intraluminal proliferation of lymphomatous cells within blood vessels.
Because of a heterogeneous clinical presentation and lack of sensitive diagnostic protocols, diagnosis of IVL is most often made at autopsy.
However, with early diagnosis and appropriate chemotherapy, the prognosis is greatly improved and complete remission is possible.
In order to broaden the possible presentations of IVL, we present a patient with an atypical manifestation of biopsy-proven intravascular large B-cell lymphoma who suffered dissections of both intracranial and extracranial arteries in addition to progressive intracranial hemorrhages.
Case Report.
A 47-year-old woman presented with unilateral paresthesias.
She developed progressive multifocal infarcts and hemorrhage with dissections of both intracranial and extracranial arteries, resulting in coma.
Brain biopsy revealed IVL.
She received aggressive chemotherapy and remains in complete remission with good neurologic recovery.
Conclusion.
IVL is known to exert its pathology on small arteries and capillaries, but is not known to cause dissections of large vessels.
The diagnosis should be considered in cases with unexplained arterial dissections and progressive strokes.
Early diagnosis with appropriate laboratory screening and tissue confirmation by biopsy can lead to greatly improved outcomes.
American Psychological Association (APA)
Chen, Ricky& Singh, Gurjeet& McNally, J. Scott& Palmer, Cheryl Ann& de Havenon, Adam. 2020. Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections. Case Reports in Neurological Medicine،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1148926
Modern Language Association (MLA)
Chen, Ricky…[et al.]. Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections. Case Reports in Neurological Medicine No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1148926
American Medical Association (AMA)
Chen, Ricky& Singh, Gurjeet& McNally, J. Scott& Palmer, Cheryl Ann& de Havenon, Adam. Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections. Case Reports in Neurological Medicine. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1148926
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148926