Plexiform Schwannoma of the Tongue in a Pediatric Patient with Neurofibromatosis Type 2: A Case Report and Review of Literature
Joint Authors
Clement, Cecilia
Amer, Samir M.
Ukudeyeva, Aijan
Pine, Harold S.
Campbell, Gerald A.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Plexiform schwannoma is a rare variant of schwannoma that accounts for only 5% of all schwannomas.
Herein, we present a rare case of plexiform schwannoma of the tongue in a pediatric patient with neurofibromatosis type 2 (NF2).
Case Presentation.
A 13-year-old female presented with a growing left-sided tongue mass.
The patient has a past medical history of NF2.
The tongue mass was excised and histopathological examination revealed a spindle cell tumor with multinodular growth pattern, with Verocay bodies' formation.
Tumor cells were strongly positive for S-100 protein and negative for smooth muscle actin (SMA), and EMA highlighted perineural fibroblasts surrounding tumor nodules.
These findings were diagnostic of plexiform schwannoma.
Conclusion.
Plexiform schwannoma of the tongue is an extremely rare tumor seen in patients with NF2.
Clinical examination and histopathological evaluation are important for diagnosis of plexiform schwannoma.
American Psychological Association (APA)
Amer, Samir M.& Ukudeyeva, Aijan& Pine, Harold S.& Campbell, Gerald A.& Clement, Cecilia. 2018. Plexiform Schwannoma of the Tongue in a Pediatric Patient with Neurofibromatosis Type 2: A Case Report and Review of Literature. Case Reports in Pathology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1148969
Modern Language Association (MLA)
Amer, Samir M.…[et al.]. Plexiform Schwannoma of the Tongue in a Pediatric Patient with Neurofibromatosis Type 2: A Case Report and Review of Literature. Case Reports in Pathology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1148969
American Medical Association (AMA)
Amer, Samir M.& Ukudeyeva, Aijan& Pine, Harold S.& Campbell, Gerald A.& Clement, Cecilia. Plexiform Schwannoma of the Tongue in a Pediatric Patient with Neurofibromatosis Type 2: A Case Report and Review of Literature. Case Reports in Pathology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1148969
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148969