The Effect of Modified Sini Decoction on Survival Rates of Patients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure
Joint Authors
Hu, Xiao-Yu
Luo, Jian-Xing
Zhang, Yang
Yu, Chang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim of the Study.
To verify the effect of modified sini decoction on patients with hepatitis B virus related acute-on-chronic liver failure.
Materials and Methods.
A retrospective cohort study was conducted.
Patients who had been treated with modified sini decoction and standard comprehensive internal medicine were assigned to an observation group, and patients who had been treated with standard comprehensive internal medicine were selected as a control group.
The total bilirubin (TBIL), albumin (ALB), alanine aminotransferase (ALT), prothrombin activity (PTA), CTP, and MELD scores were analyzed at weeks 4, 8, and 12 after treatment, respectively.
Meanwhile, the 12-week survival rate was analyzed.
Results.
The levels of TBIL and ALT were remarkably decreased, while the levels of ALB and PTA were remarkably increased in both groups at weeks 4, 8, and 12 after treatment, respectively, but the effects in the observation group were greater (P < 0.05).
The CTP and MELD scores at 8-week and 12-week were lower in the observation group than in the control group (P < 0.05).
At 12 weeks, the mean survival times of the observation group and the control group were 66.7 and 45.5 d, respectively.
Significant improvement of 12-week survival rate [39/62 (62.9%) versus 18/50 (36.0%), P = 0.001] was observed in the observation group after treatment.
Conclusions.
Modified sini decoction could protect the liver function and improve the survival rates of patients with hepatitis B virus related acute-on-chronic liver failure.
American Psychological Association (APA)
Luo, Jian-Xing& Zhang, Yang& Hu, Xiao-Yu& Yu, Chang. 2019. The Effect of Modified Sini Decoction on Survival Rates of Patients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1148970
Modern Language Association (MLA)
Luo, Jian-Xing…[et al.]. The Effect of Modified Sini Decoction on Survival Rates of Patients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1148970
American Medical Association (AMA)
Luo, Jian-Xing& Zhang, Yang& Hu, Xiao-Yu& Yu, Chang. The Effect of Modified Sini Decoction on Survival Rates of Patients with Hepatitis B Virus Related Acute-on-Chronic Liver Failure. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1148970
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1148970