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Gut Microbiota, a Potential New Target for Chinese Herbal Medicines in Treating Diabetes Mellitus
Joint Authors
Yang, Maoyi
Zhang, Boxun
Yue, Rensong
Chen, Yuan
Huang, Xiaoying
Shui, Jiacheng
Peng, Yuliang
Chin, Jiawei
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The gut microbiota, as an important factor affecting host health, plays a significant role in the occurrence and development of diabetes mellitus (DM), and the mechanism may be related to excessive endotoxins, altered short-chain fatty acids (SCFAs), and disordered bile acid metabolism.
Traditional Chinese medicine (TCM) has a long history of treating DM, but its mechanism is not very clear.
Recent research has suggested that Chinese herbal medicine can improve glucose metabolism by remodeling the gut microbiota, which opens new avenues for further research on hypoglycemic mechanisms.
This review presents the recent progress of Chinese herbs, herbal extracts, and herbal compound preparations in treating DM through regulating the gut microbiota and summarizes the main mechanisms involved, namely, anti-inflammatory and antioxidative effects, protecting the intestinal barrier and inhibiting lipotoxicity.
In addition, some suggestions for improvement are also proposed.
American Psychological Association (APA)
Zhang, Boxun& Yue, Rensong& Chen, Yuan& Yang, Maoyi& Huang, Xiaoying& Shui, Jiacheng…[et al.]. 2019. Gut Microbiota, a Potential New Target for Chinese Herbal Medicines in Treating Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1149010
Modern Language Association (MLA)
Zhang, Boxun…[et al.]. Gut Microbiota, a Potential New Target for Chinese Herbal Medicines in Treating Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1149010
American Medical Association (AMA)
Zhang, Boxun& Yue, Rensong& Chen, Yuan& Yang, Maoyi& Huang, Xiaoying& Shui, Jiacheng…[et al.]. Gut Microbiota, a Potential New Target for Chinese Herbal Medicines in Treating Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1149010
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149010