Four Subgroups of Blood Stasis Syndrome Are Identified by Manifestation Cluster Analysis in Males
Joint Authors
Kang, Byoung-Kab
Ko, Mi Mi
Lee, Hoyoung
Choi, Tae-Young
Choi, Jiae
You, Sooseong
Jung, Jeeyoun
Kim, Jihyun
Shim, Eun Hyoung
Jun, Ji Hee
Lee, Ju Ah
Cha, Min Ho
Lee, Myeong Soo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Blood stasis syndrome (BSS) is an important pathological condition in traditional East Asian medicine and is associated with ischemic heart disease, cerebral vascular accident, diabetes mellitus, chronic renal failure, severe traumatic injury, and dysmenorrhea.
However, previous studies have been unable to reveal the clinical and biological characteristics or biological markers of BSS.
We hypothesized that the heterogeneity among the manifestations of BSS or non-BSS could interfere with an analysis to describe the characteristics of BSS.
In this study, male participants based on the severity of BSS-associated symptoms and signs were clustered and classified into four subgroups: BSS subgroups (1), (2), (3), and (4).
Non-BSS core subgroup was redefined using manifestation cluster analysis.
Biological characteristics of subgroups BSS(1) and BSS(2) belong to the range of the non-BSS core subgroup (1), whereas that of subgroups BSS(3) and BSS(4) are characterized by different biological parameters such as systemic inflammatory conditions and elevated D-dimer level.
Our results suggested that patients in subgroups of BSS(3) and BSS(4) are more likely to be exposed in an inflammatory state than other BSS subgroups.
We found the heterogeneity among the manifestations which could mask the characteristics of BSS and identified the clinical and biological profiles of the four BSS subgroups through comparisons of the redefined non-BSS and BSS subgroups.
This finding could provide accurate diagnostic criteria and new approaches for BSS treatments in different subgroups.
American Psychological Association (APA)
You, Sooseong& Kang, Byoung-Kab& Jung, Jeeyoun& Cha, Min Ho& Lee, Ju Ah& Lee, Myeong Soo…[et al.]. 2019. Four Subgroups of Blood Stasis Syndrome Are Identified by Manifestation Cluster Analysis in Males. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1149016
Modern Language Association (MLA)
Jung, Jeeyoun…[et al.]. Four Subgroups of Blood Stasis Syndrome Are Identified by Manifestation Cluster Analysis in Males. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1149016
American Medical Association (AMA)
You, Sooseong& Kang, Byoung-Kab& Jung, Jeeyoun& Cha, Min Ho& Lee, Ju Ah& Lee, Myeong Soo…[et al.]. Four Subgroups of Blood Stasis Syndrome Are Identified by Manifestation Cluster Analysis in Males. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1149016
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149016