A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by EstrogenGestagen Therapy
Joint Authors
Shitanaka, Shimpei
Inayama, Yoshihide
Sakai, Mie
Ohara, Tsutomu
Suginami, Koh
Yasumoto, Koji
Ogura, Jumpei
Yamanoi, Koji
Nakakita, Baku
Suzuki, Haruka
Kishimoto, Ichiro
Sagae, Yusuke
Kitawaki, Yoshimi
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A high secretion of follicle-stimulating hormone (FSH) in reproductive-aged women is unusual.
We report a case of recurrent corpus luteum hemorrhage and subsequent ovarian torsion with markedly elevated FSH levels in a reproductive-aged woman in the absence of functional gonadotroph adenoma (FGA) or premature ovarian failure (POF).
A 22-year-old nulligravid woman with a history of bilateral hemorrhagic corpus luteum and subsequent ovarian torsion presented with acute abdominal pain.
An emergency salpingo-oophorectomy of the right side was performed, and the right ovarian torsion due to hemorrhagic corpus luteum was diagnosed.
Laboratory tests revealed markedly elevated FSH levels (77.6 mIU/mL).
FGA was suspected, but no evidence of tumor was identified.
The left ovary enlarged again at one-month follow-up.
Estrogen/gestagen therapy (EGT) was started, which reduced the enlarged ovary to normal size.
Two years later, her pituitary hormonal status was evaluated in detail.
Besides markedly elevated FSH level, slightly elevated LH (31.2 mIU/mL), normal total inhibin B (35.3 pg/ml), abnormally low anti-Müllerian hormone (AMH) (<0.03 ng/mL), and poor FSH response to gonadotropin-releasing hormone stimulation test were found.
In the absence of FGA, we conclude that certain disorders of inhibitory factors for FSH function, including inhibin and AMH may exist, which could attribute to the patient’s symptoms.
EGT was very effective in suppressing the ovarian hyperactivity.
American Psychological Association (APA)
Inayama, Yoshihide& Yamanoi, Koji& Nakakita, Baku& Shitanaka, Shimpei& Ogura, Jumpei& Ohara, Tsutomu…[et al.]. 2020. A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by EstrogenGestagen Therapy. Case Reports in Obstetrics and Gynecology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1149105
Modern Language Association (MLA)
Inayama, Yoshihide…[et al.]. A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by EstrogenGestagen Therapy. Case Reports in Obstetrics and Gynecology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1149105
American Medical Association (AMA)
Inayama, Yoshihide& Yamanoi, Koji& Nakakita, Baku& Shitanaka, Shimpei& Ogura, Jumpei& Ohara, Tsutomu…[et al.]. A Case of Recurrent Hemorrhagic Corpus Luteum with Elevated Follicle-Stimulating Hormone, Controlled by EstrogenGestagen Therapy. Case Reports in Obstetrics and Gynecology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1149105
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149105