A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis
Joint Authors
Shiba, Naoko
Inaba, Yuji
Motobayashi, Mitsuo
Nishioka, Makoto
Kawasaki, Yoichiro
Noda, Shunsuke
Matsuura, Hiroki
Kobayashi, Norimoto
Matsuoka, Takafumi
Nakazawa, Yozo
Nakamura, Akinori
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Some epidemiological studies have implied a pathogenetic association between varicella zoster virus (VZV) and multiple sclerosis (MS); this, however, remains controversial.
The present report describes a case involving an immunocompetent 10-year-old girl who developed relapsing-remitting MS following the prolonged reactivation of VZV inside the first branch of the trigeminal nerve, exhibiting herpes zoster ophthalmicus with severe optic neuritis.
Symptoms related to herpes zoster ophthalmicus and MS appeared consecutively in the 10-week period after the appearance of vesicles.
This suggests that the onset of MS was triggered by some mechanism involving VZV reactivation in the first branch of the trigeminal nerve.
To the best of our knowledge, this report is the first to describe a relationship between the onset of MS and herpes zoster ophthalmicus.
Early diagnosis and aggressive antiviral therapy are important in cases of herpes zoster ophthalmicus to prevent the possible development of MS as well as visual impairment as sequela.
American Psychological Association (APA)
Shiba, Naoko& Inaba, Yuji& Motobayashi, Mitsuo& Nishioka, Makoto& Kawasaki, Yoichiro& Noda, Shunsuke…[et al.]. 2018. A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis. Case Reports in Pediatrics،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149192
Modern Language Association (MLA)
Shiba, Naoko…[et al.]. A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis. Case Reports in Pediatrics No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1149192
American Medical Association (AMA)
Shiba, Naoko& Inaba, Yuji& Motobayashi, Mitsuo& Nishioka, Makoto& Kawasaki, Yoichiro& Noda, Shunsuke…[et al.]. A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis. Case Reports in Pediatrics. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149192
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149192