Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers
Joint Authors
Hayashi, Masaru
Nakajima, Rie
Togo, Atsuko
Kanno, Yasuhira
Mitsuzuka, Kanako
Ishimoto, Hitoshi
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
We report a case of acquired factor XI deficiency with lupus anticoagulant (LA) in a 28-year-old primigravida who presented with finger pain and eruptions on her palms and fingers during the 3rd trimester of pregnancy.
The patient complained of pain and reddening of the fingers at 30 weeks of gestation.
She was referred to our tertiary center with a diagnosis of preeclampsia and suspected collagen disease at 35 weeks of gestation.
Erythema was seen on the fingers and palms, and she presented with pain and cryesthesia on the fingers.
Laboratory investigations revealed an activated partial thromboplastin time of 51 s (normal, 23–40 s), although it was normal during the 30th and 34th gestational weeks, LA with an anticardiolipin-beta2-glycoprotein I complex antibody, and low level of clotting XI activity (25 U/mL).
On week 37 day 0 of gestation, the patient presented with severe hypertension.
An urgent Cesarean section was performed after transfusion of two units of fresh frozen plasma.
There was no excessive bleeding during the surgery or the postpartum period.
The symptoms on her fingers and palms gradually improved after surgery.
Our case indicates that dermatoses of pregnancy may become a starting point for the diagnosis of autoimmune diseases and coagulation abnormalities.
When a patient presents with an atypical symptom, as in our case, the possibility of various diseases should be considered.
American Psychological Association (APA)
Nakajima, Rie& Togo, Atsuko& Kanno, Yasuhira& Hayashi, Masaru& Mitsuzuka, Kanako& Ishimoto, Hitoshi. 2020. Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers. Case Reports in Obstetrics and Gynecology،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149224
Modern Language Association (MLA)
Nakajima, Rie…[et al.]. Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers. Case Reports in Obstetrics and Gynecology No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1149224
American Medical Association (AMA)
Nakajima, Rie& Togo, Atsuko& Kanno, Yasuhira& Hayashi, Masaru& Mitsuzuka, Kanako& Ishimoto, Hitoshi. Acquired Factor XI Deficiency with Lupus Anticoagulant in a Pregnant Woman Diagnosed by the Eruptions and Pain in Fingers. Case Reports in Obstetrics and Gynecology. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149224
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149224