The Diagnosing Challenge of a Positive ANCA Vasculitis in the Paediatric Age
Joint Authors
Mota, Conceição
Preto, Clara
Silva, Armandina
Alves, Sandra
Guedes, Margarida
Matos, Paula
Rocha, Paula
Fernandes, Paula C.
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
ANCA-positive systemic vasculitides, rare in paediatric age, present multiorganic involvement.
A female teenager presented with a history of subglottic stenosis diagnosed at the age of 12.
From the investigation carried out, we highlight hematoproteinuria and negative ANCAs.
At 15 years old, she was admitted for gastrointestinal symptoms and respiratory distress.
She presented poor peripheral perfusion, pulmonary haemorrhage, respiratory failure, and severe renal insufficiency.
She was started mechanical ventilation and emergency haemodialysis.
The immunological study revealed ANCA MPO positive.
A presumptive diagnosis of ANCA-positive vasculitis was made, and she was started corticotherapy, cyclophosphamide, and plasmapheresis.
A renal biopsy, performed later, showed crescentic glomerulonephritis with chronicity signs.
Positive ANCA vasculitis may progress slowly or suddenly.
The diagnosis was confirmed by a biopsy; however, we can make a presumptive diagnosis based on clinical findings and in a positive ANCA test in order to start an early treatment and decrease the associated morbimortality.
American Psychological Association (APA)
Preto, Clara& Silva, Armandina& Alves, Sandra& Guedes, Margarida& Matos, Paula& Mota, Conceição…[et al.]. 2017. The Diagnosing Challenge of a Positive ANCA Vasculitis in the Paediatric Age. Case Reports in Pediatrics،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1149278
Modern Language Association (MLA)
Preto, Clara…[et al.]. The Diagnosing Challenge of a Positive ANCA Vasculitis in the Paediatric Age. Case Reports in Pediatrics No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1149278
American Medical Association (AMA)
Preto, Clara& Silva, Armandina& Alves, Sandra& Guedes, Margarida& Matos, Paula& Mota, Conceição…[et al.]. The Diagnosing Challenge of a Positive ANCA Vasculitis in the Paediatric Age. Case Reports in Pediatrics. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1149278
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149278