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Ductal Adenocarcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland: a Rare and Morbid Malignancy
Joint Authors
Sivapiragasam, Abirami
Mirchia, Kanish
Ashok Kumar, Prashanth
Paulraj, Shweta
Hahn, Seung Shin
Source
Case Reports in Oncological Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Carcinoma ex pleomorphic adenoma (Ca ex PA) is a rare malignant transformation of a benign primary pleomorphic adenoma (PA).
We report the case of a 62-year-old male who presented with a swelling over his left temple.
Imaging revealed a lytic lesion over the left orbital wall with soft tissue extension suggestive of malignancy.
He underwent an en bloc resection of the mass with orbital exenteration, craniotomy, and reconstruction.
Pathology demonstrated a lacrimal gland ductal adenocarcinoma arising from a PA which led to the diagnosis of ductal adenoCa ex PA.
Postoperatively, he received chemotherapy with 6 cycles of cisplatin and concurrent radiation therapy (RT), but his course was complicated by recurrent bacterial meningitis and abscesses and he ultimately opted for comfort measures.
Patients with PA of the lacrimal gland experience an insidiously enlarging painless swelling of the orbit with transformation to Ca ex PA highlighted by a rapid onset of bulbar enlargement, displacement, and often proptosis.
Ductal adenoCa ex PA is aggressive with a poor prognosis and has no established standard of care.
This case highlights the rarity of this condition and the need for more literature to help direct treatment.
American Psychological Association (APA)
Ashok Kumar, Prashanth& Paulraj, Shweta& Mirchia, Kanish& Hahn, Seung Shin& Sivapiragasam, Abirami. 2020. Ductal Adenocarcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland: a Rare and Morbid Malignancy. Case Reports in Oncological Medicine،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1149329
Modern Language Association (MLA)
Ashok Kumar, Prashanth…[et al.]. Ductal Adenocarcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland: a Rare and Morbid Malignancy. Case Reports in Oncological Medicine No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1149329
American Medical Association (AMA)
Ashok Kumar, Prashanth& Paulraj, Shweta& Mirchia, Kanish& Hahn, Seung Shin& Sivapiragasam, Abirami. Ductal Adenocarcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland: a Rare and Morbid Malignancy. Case Reports in Oncological Medicine. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1149329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149329