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Meta-Analysis of Xihuang Pill Efficacy When Combined with Chemotherapy for Treatment of Breast Cancer
Joint Authors
Peng, Weijun
Mao, Dan
Feng, Lei
Huang, Siqi
Zhang, Shaofan
Zhang, Sifang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-12
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Objective.
To systematically evaluate the efficacy of Xihuang pill (XHP) in breast cancer patients receiving chemotherapy.
Methods.
Three English and four Chinese databases were searched.
Literature was screened using EndNote X7 and data were analyzed by Review Manager.
Results.
This review included 13 randomized clinical studies of 1272 patients.
The results showed that XHP increased the tumor response [risk ratio (RR) = 2.91; 95% confidence interval (CI): 1.98-4.26] and improved Karnofsky performance score (KPS) for breast cancer patients receiving chemotherapy [RR = 4.96; 95% CI = 2.07-11.86].
In addition, XHP treatment significantly reduced chemotherapy-induced adverse events, including nausea and vomiting [RR = 0.50; 95% CI = 0.33-0.74], WBC reduction [RR = 0.71; 95% CI = 0.47-1.06], platelet reduction [RR = 0.53; 95% CI = 0.19-1.44], hemoglobin reduction [RR = 0.31; 95% CI = 0.19-0.52], and hepatic function damage [RR = 0.63; 95% CI = 0.35-1.11].
Conclusion.
XHP combined with chemotherapy in comparison with chemotherapy alone could significantly enhance the tumor response, improve KPS, and alleviate toxicity induced by chemotherapy in breast cancer patients.
American Psychological Association (APA)
Mao, Dan& Feng, Lei& Huang, Siqi& Zhang, Shaofan& Peng, Weijun& Zhang, Sifang. 2019. Meta-Analysis of Xihuang Pill Efficacy When Combined with Chemotherapy for Treatment of Breast Cancer. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1149434
Modern Language Association (MLA)
Mao, Dan…[et al.]. Meta-Analysis of Xihuang Pill Efficacy When Combined with Chemotherapy for Treatment of Breast Cancer. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1149434
American Medical Association (AMA)
Mao, Dan& Feng, Lei& Huang, Siqi& Zhang, Shaofan& Peng, Weijun& Zhang, Sifang. Meta-Analysis of Xihuang Pill Efficacy When Combined with Chemotherapy for Treatment of Breast Cancer. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1149434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149434