Neonatal Liver Failure and Congenital Cirrhosis due to Gestational Alloimmune Liver Disease: A Case Report and Literature Review
Joint Authors
Cerski, Carlos Thadeu S.
Roos Mariano da Rocha, Carolina
Rostirola Guedes, Renata
Kieling, Carlos Oscar
Rossato Adami, Marina
Gonçalves Vieira, Sandra Maria
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Neonatal liver failure (NLF) is a major cause of neonatal morbidity and mortality, presenting as acute liver failure and/or congenital cirrhosis.
Many affected patients show antenatal signs of fetal injury.
There are several causes of NLF and early diagnosis is mandatory to elucidate the etiology and determine a specific treatment or the best management strategy.
Gestational alloimmune liver disease associated with neonatal hemochromatosis (GALD-NH) is a rare but potentially treatable cause of NLF.
It should be considered in any neonate with fetal signs of disease and postnatal signs of liver failure with no other identifiable causes.
GALD-NH is often diagnosed late and patients are therefore referred late to specialized centers, delaying treatment.
This case highlights the consequences of late diagnosis and treatment of GALD-NH and emphasizes the importance of a high grade of suspicion of this disease in order to refer the patient to a specialized center soon enough to perform the appropriate treatment.
American Psychological Association (APA)
Roos Mariano da Rocha, Carolina& Rostirola Guedes, Renata& Kieling, Carlos Oscar& Rossato Adami, Marina& Cerski, Carlos Thadeu S.& Gonçalves Vieira, Sandra Maria. 2017. Neonatal Liver Failure and Congenital Cirrhosis due to Gestational Alloimmune Liver Disease: A Case Report and Literature Review. Case Reports in Pediatrics،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1149454
Modern Language Association (MLA)
Roos Mariano da Rocha, Carolina…[et al.]. Neonatal Liver Failure and Congenital Cirrhosis due to Gestational Alloimmune Liver Disease: A Case Report and Literature Review. Case Reports in Pediatrics No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1149454
American Medical Association (AMA)
Roos Mariano da Rocha, Carolina& Rostirola Guedes, Renata& Kieling, Carlos Oscar& Rossato Adami, Marina& Cerski, Carlos Thadeu S.& Gonçalves Vieira, Sandra Maria. Neonatal Liver Failure and Congenital Cirrhosis due to Gestational Alloimmune Liver Disease: A Case Report and Literature Review. Case Reports in Pediatrics. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1149454
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149454