Inflammatory Myeloradiculitis Secondary to Pembrolizumab: A Case Report and Literature Review
Joint Authors
Vickers, M. L.
Seidl, B.
Bigby, K.
Chern, B.
Eriksson, L.
Hartnett, G.
Gericke, C.
Chew, R.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Immune checkpoint inhibitors are the most important new medications in oncology and include inhibitors of programmed cell death protein-1 (PD-1) such as Pembrolizumab, Nivolumab, and Cemiplimab.
These anticancer agents prevent tumour immune evasion and have been associated with a range of immune-related adverse events (irAEs) including those involving the nervous system.
In this case report and literature review, we present the first case of inflammatory myeloradiculitis secondary to Pembrolizumab.
We also summarise the characteristics, treatment, and outcomes of other cases reported in the literature which include a component of myelitis.
Finally, we make general recommendations on management.
American Psychological Association (APA)
Vickers, M. L.& Seidl, B.& Bigby, K.& Chern, B.& Eriksson, L.& Hartnett, G.…[et al.]. 2020. Inflammatory Myeloradiculitis Secondary to Pembrolizumab: A Case Report and Literature Review. Case Reports in Oncological Medicine،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1149511
Modern Language Association (MLA)
Vickers, M. L.…[et al.]. Inflammatory Myeloradiculitis Secondary to Pembrolizumab: A Case Report and Literature Review. Case Reports in Oncological Medicine No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1149511
American Medical Association (AMA)
Vickers, M. L.& Seidl, B.& Bigby, K.& Chern, B.& Eriksson, L.& Hartnett, G.…[et al.]. Inflammatory Myeloradiculitis Secondary to Pembrolizumab: A Case Report and Literature Review. Case Reports in Oncological Medicine. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1149511
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149511