Atypical Myocardial Infarction with Apical Thrombus and Systemic Embolism: A Rare Presentation of Likely JAK2 V617F-Positive Myeloproliferative Neoplasm
Joint Authors
Rotatori, Francesco
Muzangwa, Lloyd
Atere, Muhammed
Al-Zakhari, Rana
Collins, Jennifer
Source
Case Reports in Oncological Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
A few types of myeloproliferative neoplasms may be significant for Janus-associated kinase 2 mutation, JAK2 V617F, including polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
The prevalence of JAK2 mutation is low in the general population but higher in patients with myeloproliferative neoplasms.
Some patients with JAK2 V617F-positive essential thrombocythemia are asymptomatic, but others may develop hemorrhagic or thromboembolic complications.
Thromboembolism may occur in vessels of high flow organs like the heart and, thereby, present as myocardial infarction.
Nonetheless, these patients are usually symptomatic with complaints of chest pain, for example.
Atypical (asymptomatic) myocardial infarction with mild thrombocytosis may be the first clue for possible essential thrombocythemia with JAK2 V617F.
In this report, we discuss a case of atypical (asymptomatic) myocardial infarction with secondary thromboembolism in a patient positive for JAK2 V617F with a likely myeloproliferative neoplasm.
American Psychological Association (APA)
Atere, Muhammed& Al-Zakhari, Rana& Collins, Jennifer& Rotatori, Francesco& Muzangwa, Lloyd. 2020. Atypical Myocardial Infarction with Apical Thrombus and Systemic Embolism: A Rare Presentation of Likely JAK2 V617F-Positive Myeloproliferative Neoplasm. Case Reports in Oncological Medicine،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149546
Modern Language Association (MLA)
Atere, Muhammed…[et al.]. Atypical Myocardial Infarction with Apical Thrombus and Systemic Embolism: A Rare Presentation of Likely JAK2 V617F-Positive Myeloproliferative Neoplasm. Case Reports in Oncological Medicine No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1149546
American Medical Association (AMA)
Atere, Muhammed& Al-Zakhari, Rana& Collins, Jennifer& Rotatori, Francesco& Muzangwa, Lloyd. Atypical Myocardial Infarction with Apical Thrombus and Systemic Embolism: A Rare Presentation of Likely JAK2 V617F-Positive Myeloproliferative Neoplasm. Case Reports in Oncological Medicine. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149546
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149546