An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis

Joint Authors

Farah, Edgard
Callet, Marie
Leclerc, Augustin
Rotsos, Tryfon
Symeonidis, Chrysanthos
Jacomet, Pierre-Vincent
Galatoire, Olivier

Source

Case Reports in Ophthalmological Medicine

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-12-30

Country of Publication

Egypt

No. of Pages

3

Main Topic

Diseases

Abstract EN

Actinic keratosis is considered a precancerous lesion, constituting a precursor to squamous cell carcinoma (SCC) formation.

Perineural invasion has been observed in patients with cutaneous carcinoma due to local subcutaneous tissue destruction and primarily involves the trigeminal nerve due to rich innervation provided by the supraorbital nerve in addition to the facial nerve.

An unusual case of perineural infiltration and orbital invasion of squamous cell carcinoma associated with actinic keratosis is presented.

A 70-year-old Caucasian woman presented with complete left eye ophthalmoplegia, total left upper-eyelid ptosis, and facial pain with paresthesia.

Computed tomography revealed a process of the soft tissues in the left cheek infiltrating the infraorbital canal, pterygopalatine fossa, inferior orbital fissure, and left cavernous sinus with periosteal adherence.

Magnetic resonance imaging revealed pathological extension via the left infraorbital canal with a considerable area of necrosis.

Treatment of facial actinic keratosis may not prevent malignant transformation and can delay diagnosis and treatment of SCC.

A deep biopsy appears to be essential for a correct diagnosis.

Perineural spread of cutaneous SCC may be characterized by insidious progression in the cranial trigeminal nerve, abnormal ocular motility, diplopia, or external ophthalmoplegia.

American Psychological Association (APA)

Farah, Edgard& Callet, Marie& Leclerc, Augustin& Rotsos, Tryfon& Symeonidis, Chrysanthos& Jacomet, Pierre-Vincent…[et al.]. 2020. An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis. Case Reports in Ophthalmological Medicine،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1149696

Modern Language Association (MLA)

Farah, Edgard…[et al.]. An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis. Case Reports in Ophthalmological Medicine No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1149696

American Medical Association (AMA)

Farah, Edgard& Callet, Marie& Leclerc, Augustin& Rotsos, Tryfon& Symeonidis, Chrysanthos& Jacomet, Pierre-Vincent…[et al.]. An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis. Case Reports in Ophthalmological Medicine. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1149696

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1149696