Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease
Joint Authors
Moroz, Krzysztof
Sabol, Rachel A.
Bubenzer, Virginia
Halat, Shams
Dang, Audrey
Ferdinand, Keith
Traylor, Angela
Boyd, Carol
Harris, Kendra
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-07
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
IgG4-related ophthalmic disease is a rare, newly recognized entity with high failure rates on first-line therapy of systemic corticosteroids and no other proven management options.
Case Presentation.
Here, we present the clinical course of a patient with IgG4 ophthalmic disease who achieved a favorable response from radiotherapy.
Our patient initially presented with a history of recurrent painful flares of orbital inflammation, a pathologic diagnosis follicular lymphoid hyperplasia from a right lacrimal gland biopsy, and MRI imaging noting expansion of the lateral rectus muscle of the right eye.
Initial treatment with dacryoadenectomy and multiple courses of corticosteroids failed to keep his symptoms at bay.
Further evaluation revealed florid IgG4 staining.
In this context, he was evaluated for image-guided intensity-modulated radiotherapy (IG-IMRT) to the orbit to 20 Gy in 10 fractions.
His ophthalmic symptoms resolved.
Conclusions.
This treatment experience suggests radiotherapy may be a favorable option for symptom relief in patients with IgG4-related ophthalmic disease not controlled by corticosteroids.
American Psychological Association (APA)
Sabol, Rachel A.& Bubenzer, Virginia& Moroz, Krzysztof& Halat, Shams& Dang, Audrey& Ferdinand, Keith…[et al.]. 2020. Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease. Case Reports in Ophthalmological Medicine،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149717
Modern Language Association (MLA)
Sabol, Rachel A.…[et al.]. Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease. Case Reports in Ophthalmological Medicine No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1149717
American Medical Association (AMA)
Sabol, Rachel A.& Bubenzer, Virginia& Moroz, Krzysztof& Halat, Shams& Dang, Audrey& Ferdinand, Keith…[et al.]. Image-Guided Intensity-Modulated Radiation Therapy for IgG4-Related Ophthalmic Disease. Case Reports in Ophthalmological Medicine. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1149717
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149717