Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery
Joint Authors
Shah, Aditya
Saunders-Kurban, Meghan
Rachid, Mohamad
Ahmad, Khansa
Fatima, Aelia
Nahhas, Anas
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Daptomycin is a cyclic lipopeptide antibiotic that provides great coverage for gram positive cocci.
From the early years of daptomycin use, concerns were raised regarding the pulmonary side effects of daptomycin and potential development of acute eosinophilic pneumonia (AEP) secondary to daptomycin therapy.
Discussion.
AEP could be idiopathic or induced by drugs or toxins.
It is a distinct entity from atopic diseases and autoimmune, parasitic, or fungal infections that can also cause pulmonary eosinophilia.
Multiple medications are associated with acute eosinophilic pneumonia.
Multiple cases of daptomycin-induced AEP have been reported in the literature.
Diagnosis of AEP is based on clinical history, laboratory tests, and radiographic studies.
Obtaining bronchoalveolar lavage or lung biopsy is needed to confirm the diagnosis.
Timing of the drug use and clinical presentation is crucial in the diagnosis of drug-induced AEP.
Discontinuation of the offending drug and systemic corticosteroids are the mainstay treatment with great outcomes and recovery.
Conclusion.
We present a case of AEP caused by daptomycin, with complete recovery after discontinuation of daptomycin and administration of steroids.
The patient had AEP after almost 6 weeks of daptomycin therapy which has never been reported in literature and our patient achieved complete recovery with appropriate management.
American Psychological Association (APA)
Rachid, Mohamad& Ahmad, Khansa& Saunders-Kurban, Meghan& Fatima, Aelia& Shah, Aditya& Nahhas, Anas. 2017. Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery. Case Reports in Pulmonology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1149738
Modern Language Association (MLA)
Rachid, Mohamad…[et al.]. Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery. Case Reports in Pulmonology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1149738
American Medical Association (AMA)
Rachid, Mohamad& Ahmad, Khansa& Saunders-Kurban, Meghan& Fatima, Aelia& Shah, Aditya& Nahhas, Anas. Daptomycin-Induced Acute Eosinophilic Pneumonia: Late Onset and Quick Recovery. Case Reports in Pulmonology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1149738
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149738