Raloxifene Has No Efficacy in Reducing the High Bone Turnover and the Risk of Spontaneous Vertebral Fractures after Denosumab Discontinuation
Joint Authors
Gonzalez-Rodriguez, Elena
Stoll, Delphine
Lamy, Olivier
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
At denosumab discontinuation, an antiresorptive agent is prescribed to reduce the high bone turnover, the rapid bone loss, and the risk of spontaneous vertebral fractures.
We report the case of a woman treated with aromatase inhibitors and denosumab for 5 years.
Raloxifene was then prescribed to prevent the rebound effect.
Raloxifene was ineffective to reduce the high bone turnover and to avoid spontaneous clinical vertebral fractures.
We believe that among the antiresorptive treatments, the most powerful bisphosphonates should be favored, and their administration adapted according to the serial follow-up of bone markers.
American Psychological Association (APA)
Gonzalez-Rodriguez, Elena& Stoll, Delphine& Lamy, Olivier. 2018. Raloxifene Has No Efficacy in Reducing the High Bone Turnover and the Risk of Spontaneous Vertebral Fractures after Denosumab Discontinuation. Case Reports in Rheumatology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149845
Modern Language Association (MLA)
Gonzalez-Rodriguez, Elena…[et al.]. Raloxifene Has No Efficacy in Reducing the High Bone Turnover and the Risk of Spontaneous Vertebral Fractures after Denosumab Discontinuation. Case Reports in Rheumatology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1149845
American Medical Association (AMA)
Gonzalez-Rodriguez, Elena& Stoll, Delphine& Lamy, Olivier. Raloxifene Has No Efficacy in Reducing the High Bone Turnover and the Risk of Spontaneous Vertebral Fractures after Denosumab Discontinuation. Case Reports in Rheumatology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1149845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149845