Eltrombopag Improves Refractory Thrombocytopenia in a Patient with Systemic Lupus Erythematosus
Joint Authors
Ohashi, Kenichi
Shima, Natsuki
Sumida, Keiichi
Kawada, Masahiro
Sekine, Akinari
Yamanouchi, Masayuki
Hiramatsu, Rikako
Hayami, Noriko
Hasegawa, Eiko
Suwabe, Tatsuya
Hoshino, Junichi
Sawa, Naoki
Takaichi, Kenmei
Fujii, Takeshi
Ubara, Yoshifumi
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A 42-year-old woman with systemic lupus erythematosus (SLE) was admitted to our hospital for evaluation of severe thrombocytopenia.
She was treated with steroids, intravenous cyclophosphamide, intravenous immunoglobulin, and plasma exchange, but her thrombocytopenia did not improve.
Renal biopsy showed class IV-S(C) + V lupus nephritis, according to the classification of the International Society of Nephrology/Renal Pathology Society.
The PA-IgG and serum thrombopoietin (TPO) levels were elevated.
Her thrombocytopenia responded to off-label administration of eltrombopag, which was discontinued after 42 months.
At 18 months after stopping eltrombopag, the platelet count was 19.3 × 104/μL.
Eltrombopag may be a therapeutic option for SLE patients with severe thrombocytopenia refractory to conventional therapy.
American Psychological Association (APA)
Shima, Natsuki& Sumida, Keiichi& Kawada, Masahiro& Sekine, Akinari& Yamanouchi, Masayuki& Hiramatsu, Rikako…[et al.]. 2018. Eltrombopag Improves Refractory Thrombocytopenia in a Patient with Systemic Lupus Erythematosus. Case Reports in Rheumatology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1149864
Modern Language Association (MLA)
Shima, Natsuki…[et al.]. Eltrombopag Improves Refractory Thrombocytopenia in a Patient with Systemic Lupus Erythematosus. Case Reports in Rheumatology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1149864
American Medical Association (AMA)
Shima, Natsuki& Sumida, Keiichi& Kawada, Masahiro& Sekine, Akinari& Yamanouchi, Masayuki& Hiramatsu, Rikako…[et al.]. Eltrombopag Improves Refractory Thrombocytopenia in a Patient with Systemic Lupus Erythematosus. Case Reports in Rheumatology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1149864
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1149864